ENSMUSG00000003153


Mus musculus

Features
Gene ID: ENSMUSG00000003153
  
Biological name :Slc2a3
  
Synonyms : P32037 / Slc2a3 / solute carrier family 2 (facilitated glucose transporter), member 3
  
Possible biological names infered from orthology : P11169 / Q8TDB8 / SLC2A14 / solute carrier family 2 member 14 / solute carrier family 2 member 3
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F1
Gene start: 122727809
Gene end: 122801640
  
Corresponding Affymetrix probe sets: 10547641 (MoGene1.0st)   1421924_at (Mouse Genome 430 2.0 Array)   1427770_a_at (Mouse Genome 430 2.0 Array)   1437052_s_at (Mouse Genome 430 2.0 Array)   1455898_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032476
Ensembl peptide - ENSMUSP00000132586
Ensembl peptide - ENSMUSP00000131615
Ensembl peptide - ENSMUSP00000129925
Ensembl peptide - ENSMUSP00000129604
Ensembl peptide - ENSMUSP00000128076
NCBI entrez gene - 20527     See in Manteia.
MGI - MGI:95757
RefSeq - XM_011241268
RefSeq - NM_011401
RefSeq - XM_006505822
RefSeq - XM_006505823
RefSeq Peptide - NP_035531
swissprot - E9Q6T5
swissprot - P32037
swissprot - Q3TPL8
swissprot - E9Q2G7
swissprot - E9PZF2
swissprot - E9Q4C4
swissprot - E9PX20
Ensembl - ENSMUSG00000003153
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC2A14ENSGALG00000014324Gallus gallus
 P11169ENSG00000059804Homo sapiens
 Q8TDB8ENSG00000173262Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P17809 / Slc2a1 / solute carrier family 2 (facilitated glucose transporter), member 1 / P11166* / solute carrier family 2 member 1*ENSMUSG0000002864565
P14142 / Slc2a4 / solute carrier family 2 (facilitated glucose transporter), member 4 / P14672* / solute carrier family 2 member 4*ENSMUSG0000001856657
P14246 / Slc2a2 / solute carrier family 2 (facilitated glucose transporter), member 2 / P11168* / solute carrier family 2 member 2*ENSMUSG0000002769048
Q9WV38 / Slc2a5 / solute carrier family 2 (facilitated glucose transporter), member 5 / P22732* / solute carrier family 2 member 5*ENSMUSG0000002897642
Slc2a7 / solute carrier family 2 (facilitated glucose transporter), member 7 / Q6PXP3* / solute carrier family 2 member 7*ENSMUSG0000006206441
Slc2a9 / solute carrier family 2 (facilitated glucose transporter), member 9 / Q9NRM0* / solute carrier family 2 member 9*ENSMUSG0000000510738


Protein motifs (from Interpro)
Interpro ID Name
 IPR002945  Glucose transporter, type 3 (GLUT3)
 IPR003663  Sugar/inositol transporter
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070837 dehydroascorbic acid transport IDA
 biological_processGO:1904659 glucose transmembrane transport IEA
 cellular_componentGO:0002080 acrosomal membrane IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005355 glucose transmembrane transporter activity IEA
 molecular_functionGO:0005536 glucose binding ISO
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0033300 dehydroascorbic acid transmembrane transporter activity ISO
 molecular_functionGO:0055056 D-glucose transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Cellular hexose transport
Vitamin C (ascorbate) metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lpin1fld/Lpin1fld
Genetic Background: BALB/cByJ-Lpin1fld

 MP:0004265 abnormal placental transport "anomaly in the conveyance of metabolic products and nutrients across the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lpin1fld/Lpin1fld
Genetic Background: BALB/cByJ-Lpin1fld

 MP:0004994 abnormal brain wave pattern "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Lpin1fld/Lpin1fld
Genetic Background: BALB/cByJ-Lpin1fld

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
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Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003153 P32037 / Slc2a3 / solute carrier family 2 (facilitated glucose transporter), member 3 / P11169* / Q8TDB8* / SLC2A14* / solute carrier family 2 member 3* / solute carrier family 2 member 14*  / complex






 

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