ENSMUSG00000004894


Mus musculus

Features
Gene ID: ENSMUSG00000004894
  
Biological name :Hapln2
  
Synonyms : Hapln2 / hyaluronan and proteoglycan link protein 2 / Q9ESM3
  
Possible biological names infered from orthology : Q9GZV7
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 88021750
Gene end: 88027583
  
Corresponding Affymetrix probe sets: 10499299 (MoGene1.0st)   1420962_at (Mouse Genome 430 2.0 Array)   1420963_at (Mouse Genome 430 2.0 Array)   1435629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005014
Ensembl peptide - ENSMUSP00000125271
NCBI entrez gene - 73940     See in Manteia.
MGI - MGI:2137300
RefSeq - NM_022031
RefSeq - XM_006502148
RefSeq Peptide - NP_071314
swissprot - E0CXI3
swissprot - B2RRU7
swissprot - Q9ESM3
Ensembl - ENSMUSG00000004894
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hapln2ENSDARG00000003903Danio rerio
 HAPLN2ENSGALG00000013234Gallus gallus
 HAPLN2ENSG00000132702Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hapln3 / Q80WM5 / Hyaluronan and proteoglycan link protein 3 / Q96S86*ENSMUSG0000003060647
Hapln4 / Q80WM4 / Hyaluronan and proteoglycan link protein 4 / Q86UW8*ENSMUSG0000000759445
Hapln1 / Q9QUP5 / Hyaluronan and proteoglycan link protein 1 / P10915*ENSMUSG0000002161343
Ncan / neurocan / O14594*ENSMUSG0000000234139
Bcan / Q61361 / Brevican core protein / Q96GW7* / brevican*ENSMUSG0000000489236
Acan / Q61282 / Aggrecan core protein / aggrecan*ENSMUSG0000003060734
Vcan / versican / P13611*ENSMUSG0000002161433
O08859 / Tnfaip6 / tumor necrosis factor alpha induced protein 6 / P98066* / TNF alpha induced protein 6*ENSMUSG0000005347517
Stab1 / stabilin 1 / Q9NY15*ENSMUSG0000004228617
Stab2 / Q8R4U0 / Stabilin-2 Short form stabilin-2 / Q8WWQ8* / stabilin 2*ENSMUSG0000003545917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000538  Link domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IBA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007417 central nervous system development IBA
 biological_processGO:0008065 establishment of blood-nerve barrier IMP
 biological_processGO:0085029 extracellular matrix assembly IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IBA
 molecular_functionGO:0005540 hyaluronic acid binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003633 abnormal nervous system physiology 
Show

Allelic Composition: Cryaatm1Ady/Cryaa+
Genetic Background: involves: 129

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cryaatm1Ady/Cryaa+
Genetic Background: involves: 129

 MP:0010748 abnormal visual evoked potential "anomaly in the electroencephalographic pattern recorded from the occipital area generated in response to retinal stimulation such as flashing lights or inverting a contrasting image; may be used to evaluate optic nerve damage or visual perception" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cryaatm1Ady/Cryaa+
Genetic Background: involves: 129

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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