ENSMUSG00000004892


Mus musculus

Features
Gene ID: ENSMUSG00000004892
  
Biological name :Bcan
  
Synonyms : Bcan / Brevican core protein / Q61361
  
Possible biological names infered from orthology : brevican / Q96GW7
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 87987531
Gene end: 88000230
  
Corresponding Affymetrix probe sets: 10499285 (MoGene1.0st)   1416718_at (Mouse Genome 430 2.0 Array)   1441899_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088491
Ensembl peptide - ENSMUSP00000141455
NCBI entrez gene - 12032     See in Manteia.
MGI - MGI:1096385
RefSeq - XM_006500937
RefSeq - NM_007529
RefSeq - XM_006500936
RefSeq Peptide - NP_031555
swissprot - Q61361
swissprot - A0A0A6YW95
Ensembl - ENSMUSG00000004892
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcanENSDARG00000099412Danio rerio
 BCANENSGALG00000045469Gallus gallus
 BCANENSG00000132692Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acan / Q61282 / Aggrecan core protein / aggrecan*ENSMUSG0000003060739
Vcan / versican / P13611*ENSMUSG0000002161439
Ncan / neurocan / O14594*ENSMUSG0000000234136
Stab1 / stabilin 1 / Q9NY15*ENSMUSG0000004228617
Stab2 / Q8R4U0 / Stabilin-2 Short form stabilin-2 / Q8WWQ8* / stabilin 2*ENSMUSG0000003545917
Hapln1 / Q9QUP5 / Hyaluronan and proteoglycan link protein 1 / P10915*ENSMUSG0000002161316
Hapln3 / Q80WM5 / Hyaluronan and proteoglycan link protein 3 / Q96S86*ENSMUSG0000003060616
Hapln4 / Q80WM4 / Hyaluronan and proteoglycan link protein 4 / Q86UW8*ENSMUSG0000000759415
Hapln2 / Q9ESM3 / hyaluronan and proteoglycan link protein 2 / Q9GZV7*ENSMUSG0000000489414
O08859 / Tnfaip6 / tumor necrosis factor alpha induced protein 6 / P98066* / TNF alpha induced protein 6*ENSMUSG000000534757


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000538  Link domain
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013032  EGF-like, conserved site
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR035976  Sushi/SCR/CCP superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IBA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0021766 hippocampus development IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005540 hyaluronic acid binding IBA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Cd28tm1Mak/Cd28tm1Mak,Tnfsf9tm1Thw/Tnfsf9tm1Thw
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0002207 abnormal long term potentiation "alterations in a persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd28tm1Mak/Cd28tm1Mak,Tnfsf9tm1Thw/Tnfsf9tm1Thw
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr