ENSMUSG00000009246


Mus musculus

Features
Gene ID: ENSMUSG00000009246
  
Biological name :Trpm5
  
Synonyms : Q9JJH7 / Transient receptor potential cation channel subfamily M member 5 / Trpm5
  
Possible biological names infered from orthology : Q9NZQ8
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F5
Gene start: 143069153
Gene end: 143094642
  
Corresponding Affymetrix probe sets: 10569399 (MoGene1.0st)   1418783_at (Mouse Genome 430 2.0 Array)   1443413_s_at (Mouse Genome 430 2.0 Array)   1449224_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009390
Ensembl peptide - ENSMUSP00000114302
Ensembl peptide - ENSMUSP00000121802
Ensembl peptide - ENSMUSP00000122685
NCBI entrez gene - 56843     See in Manteia.
MGI - MGI:1861718
RefSeq - XM_006508646
RefSeq - XM_017322383
RefSeq - XM_017322384
RefSeq - NM_020277
RefSeq - XM_006508645
RefSeq Peptide - NP_064673
swissprot - Q9JJH7
swissprot - F6RUN7
swissprot - F7CCW2
Ensembl - ENSMUSG00000009246
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpm5ENSDARG00000059792Danio rerio
 TRPM5ENSGALG00000006521Gallus gallus
 TRPM5ENSG00000070985Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpm4 / Q7TN37 / Transient receptor potential cation channel subfamily M member 4 / Q8TD43*ENSMUSG0000003826043
Trpm2 / Q91YD4 / Transient receptor potential cation channel subfamily M member 2 / O94759*ENSMUSG0000000929238
Trpm8 / Q8R4D5 / Transient receptor potential cation channel subfamily M member 8 / Q7Z2W7*ENSMUSG0000003625130
Trpm1 / Q2TV84 / Transient receptor potential cation channel subfamily M member 1 / Q7Z4N2*ENSMUSG0000003052328
Trpm3 / transient receptor potential cation channel, subfamily M, member 3 / Q9HCF6*ENSMUSG0000005238728
Trpm7 / Q923J1 / Transient receptor potential cation channel subfamily M member 7 / Q96QT4*ENSMUSG0000002736527
Trpm6 / Q8CIR4 / Transient receptor potential cation channel subfamily M member 6 / Q9BX84*ENSMUSG0000002472727


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR029577  Transient receptor potential cation channel subfamily M member 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0034220 ion transmembrane transport IDA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005227 calcium activated cation channel activity IDA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IDA
 molecular_functionGO:0005272 sodium channel activity IDA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001985 abnormal gustatory system physiology "anomalous perception of taste" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

 MP:0001986 taste sensitivity/ preferences 
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Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

Allelic Composition: Trpm5tm1Dgen/Trpm5tm1Dgen
Genetic Background: B6.129P2-Trpm5tm1Dgen

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Celsr2tm1Dgen/Celsr2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002376 abnormal dendritic cell physiology "failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:85808]
Show

Allelic Composition: Pcnatm1.1Mdsc/Pcnatm1.1Mdsc,Tg(Pcna*K164R)1Mdsc/0
Genetic Background: involves: FVB/N

 MP:0004209 abnormal sweet taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something sweet by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0004210 abnormal bitter taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something bitter by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0004211 abnormal sour taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something sour by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0004212 abnormal salty taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something salty by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0004213 abnormal unami taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something unami (savory) by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trpm5tm1Sdmk/Trpm5tm1Sdmk
Genetic Background: involves: C57BL/6

 MP:0008127 decreased dendritic cell number "reduction in the number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trpm4tm1.1Knt/Trpm4tm1.1Knt,Trpm5tm1Csz/Trpm5tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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