ENSMUSG00000052387


Mus musculus

Features
Gene ID: ENSMUSG00000052387
  
Biological name :Trpm3
  
Synonyms : transient receptor potential cation channel, subfamily M, member 3 / Trpm3
  
Possible biological names infered from orthology : Q9HCF6
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: B
Gene start: 22139119
Gene end: 22989884
  
Corresponding Affymetrix probe sets: 10462039 (MoGene1.0st)   1439026_at (Mouse Genome 430 2.0 Array)   1441966_at (Mouse Genome 430 2.0 Array)   1443723_at (Mouse Genome 430 2.0 Array)   1456633_at (Mouse Genome 430 2.0 Array)   1456923_at (Mouse Genome 430 2.0 Array)   1457927_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097160
Ensembl peptide - ENSMUSP00000084857
Ensembl peptide - ENSMUSP00000097162
Ensembl peptide - ENSMUSP00000097164
Ensembl peptide - ENSMUSP00000042184
Ensembl peptide - ENSMUSP00000074328
NCBI entrez gene - 226025     See in Manteia.
MGI - MGI:2443101
RefSeq - XM_017318158
RefSeq - XM_006526965
RefSeq - XM_006526966
RefSeq - XM_006526967
RefSeq - XM_006526968
RefSeq - XM_006526969
RefSeq - XM_006526971
RefSeq - XM_006526972
RefSeq - XM_006526974
RefSeq - XM_006526975
RefSeq - XM_006526976
RefSeq - XM_006526977
RefSeq - XM_006526978
RefSeq - XM_006526979
RefSeq - XM_011247233
RefSeq - XM_017318155
RefSeq - NM_001035239
RefSeq - NM_001035240
RefSeq - NM_001035241
RefSeq - NM_001035242
RefSeq - NM_001035243
RefSeq - NM_001035244
RefSeq - NM_001035245
RefSeq - NM_001035246
RefSeq - NM_177341
RefSeq - XM_006526954
RefSeq - XM_006526955
RefSeq - XM_006526956
RefSeq - XM_006526957
RefSeq - XM_006526958
RefSeq - XM_006526959
RefSeq - XM_006526961
RefSeq - XM_006526962
RefSeq - XM_006526963
RefSeq - XM_006526964
RefSeq Peptide - NP_001030322
RefSeq Peptide - NP_001030323
RefSeq Peptide - NP_001030316
RefSeq Peptide - NP_001030317
RefSeq Peptide - NP_001030318
RefSeq Peptide - NP_001030319
RefSeq Peptide - NP_796315
RefSeq Peptide - NP_001030320
RefSeq Peptide - NP_001030321
swissprot - Q5F4S8
swissprot - D3Z539
swissprot - E9PUC8
swissprot - Q5F4S9
swissprot - Q5F4T0
swissprot - B2RUS0
Ensembl - ENSMUSG00000052387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpm3ENSDARG00000039181Danio rerio
 TRPM3ENSGALG00000015126Gallus gallus
 TRPM3ENSG00000083067Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpm1 / Q2TV84 / Transient receptor potential cation channel subfamily M member 1 / Q7Z4N2*ENSMUSG0000003052358
Trpm7 / Q923J1 / Transient receptor potential cation channel subfamily M member 7 / Q96QT4*ENSMUSG0000002736548
Trpm6 / Q8CIR4 / Transient receptor potential cation channel subfamily M member 6 / Q9BX84*ENSMUSG0000002472742
Trpm2 / Q91YD4 / Transient receptor potential cation channel subfamily M member 2 / O94759*ENSMUSG0000000929223
Trpm4 / Q7TN37 / Transient receptor potential cation channel subfamily M member 4 / Q8TD43*ENSMUSG0000003826020
Trpm5 / Q9JJH7 / Transient receptor potential cation channel subfamily M member 5 / Q9NZQ8*ENSMUSG0000000924619
Trpm8 / Q8R4D5 / Transient receptor potential cation channel subfamily M member 8 / Q7Z2W7*ENSMUSG0000003625118


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR029583  Transient receptor potential cation channel subfamily M member 3
 IPR029588  Transient receptor potential cation channel subfamily M member 1
 IPR032415  TRPM, tetramerisation domain
 IPR037162  TRPM, tetramerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport ISO
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway IEA
 biological_processGO:0016048 detection of temperature stimulus IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0050951 sensory perception of temperature stimulus IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071482 cellular response to light stimulus IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005227 calcium activated cation channel activity IEA
 molecular_functionGO:0005261 cation channel activity ISO


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Myo6sv/Myo6sv
Genetic Background: involves: B10.HA/(33NX)Sn * SEC/1Gn

 MP:0002736 abnormal nociception after inflammation "changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myo6sv/Myo6sv
Genetic Background: involves: B10.HA/(33NX)Sn * SEC/1Gn

 MP:0003663 abnormal thermosensation "defect in the ability to sense or display a preference for a given temperature" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96549]
Show

Allelic Composition: Myo6sv/Myo6sv
Genetic Background: involves: B10.HA/(33NX)Sn * SEC/1Gn

 MP:0008531 increased chemical nociceptive threshold "a greater than average concentration at which chemically induced pain sensation is first detectable" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myo6sv/Myo6sv
Genetic Background: involves: B10.HA/(33NX)Sn * SEC/1Gn

 MP:0010055 abnormal sensory neuron physiology "any functional anomaly of cells that innervate an effector (muscle or glandular) tissue and are responsible for transmission of sensory impulses" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Myo6sv/Myo6sv
Genetic Background: involves: B10.HA/(33NX)Sn * SEC/1Gn

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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