ENSMUSG00000030523


Mus musculus

Features
Gene ID: ENSMUSG00000030523
  
Biological name :Trpm1
  
Synonyms : Q2TV84 / Transient receptor potential cation channel subfamily M member 1 / Trpm1
  
Possible biological names infered from orthology : Q7Z4N2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: C
Gene start: 64153835
Gene end: 64269775
  
Corresponding Affymetrix probe sets: 10553861 (MoGene1.0st)   1418935_at (Mouse Genome 430 2.0 Array)   1437445_at (Mouse Genome 430 2.0 Array)   1437531_at (Mouse Genome 430 2.0 Array)   1440241_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145776
Ensembl peptide - ENSMUSP00000146323
Ensembl peptide - ENSMUSP00000146265
Ensembl peptide - ENSMUSP00000146257
Ensembl peptide - ENSMUSP00000146226
Ensembl peptide - ENSMUSP00000146163
Ensembl peptide - ENSMUSP00000146140
Ensembl peptide - ENSMUSP00000146073
Ensembl peptide - ENSMUSP00000145995
Ensembl peptide - ENSMUSP00000145814
Ensembl peptide - ENSMUSP00000082318
Ensembl peptide - ENSMUSP00000134947
Ensembl peptide - ENSMUSP00000145593
Ensembl peptide - ENSMUSP00000145708
NCBI entrez gene - 17364     See in Manteia.
MGI - MGI:1330305
RefSeq - NM_001039104
RefSeq - NM_018752
RefSeq - XM_017322013
RefSeq Peptide - NP_001034193
RefSeq Peptide - NP_061222
swissprot - A0A0U1RPI6
swissprot - A0A0U1RP37
swissprot - A0A0U1RQB3
swissprot - Q2TV84
swissprot - A0A0U1RNU7
swissprot - A0A0U1RQ58
swissprot - A0A0U1RQ32
swissprot - A0A0U1RPX6
swissprot - A0A0U1RPV6
swissprot - A0A0U1RPQ0
Ensembl - ENSMUSG00000030523
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpm1aENSDARG00000011259Danio rerio
 trpm1bENSDARG00000103476Danio rerio
 TRPM1ENSGALG00000003849Gallus gallus
 TRPM1ENSG00000134160Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpm3 / transient receptor potential cation channel, subfamily M, member 3 / Q9HCF6*ENSMUSG0000005238761
Trpm7 / Q923J1 / Transient receptor potential cation channel subfamily M member 7 / Q96QT4*ENSMUSG0000002736546
Trpm6 / Q8CIR4 / Transient receptor potential cation channel subfamily M member 6 / Q9BX84*ENSMUSG0000002472742
Trpm2 / Q91YD4 / Transient receptor potential cation channel subfamily M member 2 / O94759*ENSMUSG0000000929223
Trpm4 / Q7TN37 / Transient receptor potential cation channel subfamily M member 4 / Q8TD43*ENSMUSG0000003826021
Trpm5 / Q9JJH7 / Transient receptor potential cation channel subfamily M member 5 / Q9NZQ8*ENSMUSG0000000924620
Trpm8 / Q8R4D5 / Transient receptor potential cation channel subfamily M member 8 / Q7Z2W7*ENSMUSG0000003625120


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR029588  Transient receptor potential cation channel subfamily M member 1
 IPR032415  TRPM, tetramerisation domain
 IPR037162  TRPM, tetramerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IGI
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway ISS
 biological_processGO:0007601 visual perception ISO
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0046548 retinal rod cell development IMP
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060402 calcium ion transport into cytosol ISS
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0071482 cellular response to light stimulus ISO
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035841 new growing cell tip IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005261 cation channel activity IDA
 molecular_functionGO:0005262 calcium channel activity ISO


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tlr4lps-n/Tlr4lps-n
Genetic Background: C3H/HeN

 MP:0003484 abnormal channel response "anomalies in the electrophysiological recordings from ion channels" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Trpm1tvrm27/Trpm1tvrm27
Genetic Background: involves: C57BL/6J

Allelic Composition: Trpm1tvrm27/Trpm1+
Genetic Background: involves: C57BL/6J

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tlr4lps-n/Tlr4lps-n
Genetic Background: C3H/HeN

Allelic Composition: Trpm1tm1Tfur/Trpm1tm1Tfur
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Trpm1tvrm27/Trpm1tvrm27
Genetic Background: involves: C57BL/6J

Allelic Composition: Trpm1tm1Lex/Trpm1tvrm27
Genetic Background: involves: 129S/SvEvBrd * C57BL/6J

Allelic Composition: Trpm1tvrm27/Trpm1+
Genetic Background: involves: C57BL/6J

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tlr4lps-n/Tlr4lps-n
Genetic Background: C3H/HeN

Allelic Composition: Trpm1tm1Tfur/Trpm1tm1Tfur
Genetic Background: involves: 129S6/SvEvTac

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tlr4lps-n/Tlr4lps-n
Genetic Background: C3H/HeN

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Tlr4lps-n/Tlr4lps-n
Genetic Background: C3H/HeN

Allelic Composition: Trpm1tvrm27/Trpm1tvrm27
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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