ENSMUSG00000010651


Mus musculus

Features
Gene ID: ENSMUSG00000010651
  
Biological name :Acaa1b
  
Synonyms : Acaa1b / acetyl-Coenzyme A acyltransferase 1B / Q8VCH0
  
Possible biological names infered from orthology : ACAA1 / acetyl-CoA acyltransferase 1 / P09110
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F3
Gene start: 119148023
Gene end: 119157093
  
Corresponding Affymetrix probe sets: 10597592 (MoGene1.0st)   1416946_a_at (Mouse Genome 430 2.0 Array)   1416947_s_at (Mouse Genome 430 2.0 Array)   1424451_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010795
NCBI entrez gene - 235674     See in Manteia.
MGI - MGI:3605455
RefSeq - XM_011242970
RefSeq - NM_146230
RefSeq - XM_006512114
RefSeq Peptide - NP_666342
swissprot - Q8VCH0
swissprot - Q3UKM0
Ensembl - ENSMUSG00000010651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acaa1ENSDARG00000004687Danio rerio
 ACAA1ENSGALG00000005860Gallus gallus
 ACAA1ENSG00000060971Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acaa1a / Q921H8 / acetyl-Coenzyme A acyltransferase 1A / ACAA1* / P09110* / acetyl-CoA acyltransferase 1*ENSMUSG0000003613896
Hadhb / Q99JY0 / hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit / P55084* / hydroxyacyl-CoA dehydrogena...ENSMUSG0000005944734


Protein motifs (from Interpro)
Interpro ID Name
 IPR002155  Thiolase
 IPR016039  Thiolase-like
 IPR020610  Thiolase, active site
 IPR020613  Thiolase, conserved site
 IPR020615  Thiolase, acyl-enzyme intermediate active site
 IPR020616  Thiolase, N-terminal
 IPR020617  Thiolase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003988 acetyl-CoA C-acyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA


Pathways (from Reactome)
Pathway description
alpha-linolenic acid (ALA) metabolism
Beta-oxidation of very long chain fatty acids
Neutrophil degranulation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hif1atm1Pec/Hif1atm1Pec
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020283 Pex13 / Q9D0K1 / Peroxisomal membrane protein PEX13 / Q92968* / peroxisomal biogenesis factor 13*  / complex
 ENSMUSG00000020003 Pex7 / P97865 / Peroxisomal targeting signal 2 receptor / O00628* / peroxisomal biogenesis factor 7*  / complex / reaction
 ENSMUSG00000018733 Pex12 / Q8VC48 / Peroxisome assembly protein 12 / O00623* / peroxisomal biogenesis factor 12*  / complex
 ENSMUSG00000005069 Pex5 / O09012 / Peroxisomal targeting signal 1 receptor / P50542* / peroxisomal biogenesis factor 5*  / complex
 ENSMUSG00000040374 Pex2 / peroxisomal biogenesis factor 2 / P28328*  / complex
 ENSMUSG00000029047 Pex10 / B1AUE5 / Peroxisome biosis factor 10 / O60683* / peroxisomal biogenesis factor 10*  / complex
 ENSMUSG00000028975 Pex14 / Q9R0A0 / Peroxisomal membrane protein PEX14 / O75381* / peroxisomal biogenesis factor 14*  / complex






 

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