ENSMUSG00000010803


Mus musculus

Features
Gene ID: ENSMUSG00000010803
  
Biological name :Gabra1
  
Synonyms : Gabra1 / Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), transcript variant 2, mRNA. / P62812
  
Possible biological names infered from orthology : gamma-aminobutyric acid type A receptor alpha1 subunit / P14867
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A5
Gene start: 42130939
Gene end: 42182930
  
Corresponding Affymetrix probe sets: 10385297 (MoGene1.0st)   1421280_at (Mouse Genome 430 2.0 Array)   1421281_at (Mouse Genome 430 2.0 Array)   1436889_at (Mouse Genome 430 2.0 Array)   1455766_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126611
Ensembl peptide - ENSMUSP00000147186
Ensembl peptide - ENSMUSP00000146285
Ensembl peptide - ENSMUSP00000146133
Ensembl peptide - ENSMUSP00000145949
Ensembl peptide - ENSMUSP00000129056
Ensembl peptide - ENSMUSP00000020707
NCBI entrez gene - 14394     See in Manteia.
MGI - MGI:95613
RefSeq - XM_017314260
RefSeq - XM_017314259
RefSeq - NM_010250
RefSeq - XM_006532195
RefSeq - NM_001359035
RefSeq - XM_006532196
RefSeq Peptide - NP_001345964
RefSeq Peptide - NP_034380
swissprot - E9PXL4
swissprot - P62812
swissprot - Q544F7
swissprot - A0A0U1RPE4
swissprot - A0A0U1RQ83
swissprot - A0A140LJE7
swissprot - E9Q2L8
Ensembl - ENSMUSG00000010803
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabra1ENSDARG00000068989Danio rerio
 GABRA1ENSGALG00000001698Gallus gallus
 GABRA1ENSG00000022355Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gabra2 / P26048 / Gamma-aminobutyric acid receptor subunit alpha-2 / P47869* / gamma-aminobutyric acid type A receptor alpha2 subunit*ENSMUSG0000000056076
Gabra3 / P26049 / Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 (Gabra3), transcript variant 3, mRNA. / P34903* / gamma-aminobutyric acid type A receptor alpha3 subunit*ENSMUSG0000003134371
Gabra5 / Q8BHJ7 / Gamma-aminobutyric acid receptor subunit alpha-5 / P31644* / gamma-aminobutyric acid type A receptor alpha5 subunit*ENSMUSG0000005507870
Gabra4 / Q9D6F4 / Gamma-aminobutyric acid receptor subunit alpha-4 / P48169* / gamma-aminobutyric acid type A receptor alpha4 subunit*ENSMUSG0000002921158
Gabra6 / P16305 / Gamma-aminobutyric acid receptor subunit alpha-6 / Q16445* / gamma-aminobutyric acid type A receptor alpha6 subunit*ENSMUSG0000002042855
Gabrg2 / P22723 / Gamma-aminobutyric acid receptor subunit gamma-2 / P18507* / gamma-aminobutyric acid type A receptor gamma2 subunit*ENSMUSG0000002043643
Gabrg1 / Q9R0Y8 / Gamma-aminobutyric acid receptor subunit gamma-1 / Q8N1C3* / gamma-aminobutyric acid type A receptor gamma1 subunit*ENSMUSG0000000126042
Gabrg3 / P27681 / Gamma-aminobutyric acid receptor subunit gamma-3 / Q99928* / gamma-aminobutyric acid type A receptor gamma3 subunit*ENSMUSG0000005502642
Gabre / P78334* / gamma-aminobutyric acid type A receptor epsilon subunit*ENSMUSG0000003134032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001390  Gamma-aminobutyric-acid A receptor, alpha subunit
 IPR005431  Gamma-aminobutyric-acid A receptor, alpha 1 subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0051932 synaptic transmission, GABAergic IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IMP
 biological_processGO:0071420 cellular response to histamine IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:1902710 GABA receptor complex IEA
 cellular_componentGO:1902711 GABA-A receptor complex IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0016917 GABA receptor activity IEA
 molecular_functionGO:0022851 GABA-gated chloride ion channel activity IEA
 molecular_functionGO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP


Pathways (from Reactome)
Pathway description
GABA A receptor activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000243 myoclonus "involuntary shock-like contractions, variable in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles; generally due to a central nervous system lesion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Cacna1gtm1Hssh/Cacna1gtm1Hssh,Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

 MP:0000880 decreased Purkinje cell number "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Cacna1gtm1Hssh/Cacna1gtm1Hssh,Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Ryr2tm2.1Maya/Ryr2+
Genetic Background: involves: C57BL/6J

Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: D2.129(Cg)-Gabra1tm1.1Geh

 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
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Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Map3k4tm1Flv/Map3k4+,X/SryAKR/J
Genetic Background: B6.Cg-Map3k4tm1Flv Chr YAKR

 MP:0001400 hyperresponsive "increased reaction to touch" [J:39801]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cacna1gtm1Hssh/Cacna1gtm1Hssh,Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

 MP:0001443 poor grooming "below average standard of cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [MGI:CLS, J:30404]
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Allelic Composition: Hoxc13tm3.1Mrc/Hoxc13+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: D2.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cyfip2tm1(KOMP)Vlcg/Cyfip2+,Fmr1tm1Cgr/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac

Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Mjga
Genetic Background: B6J.Cg-Gabra1tm1.1Geh Gabra1tm1.1Mjga

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Emx1tm1(cre)Ito/Emx1+,Hes1tm1Fgu/Hes1tm1Hojo,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Gabra1tm1Geh/Gabra1tm1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0002804 abnormal motor learning "defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Cacna1gtm1Hssh/Cacna1gtm1Hssh,Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Itgb6tm1Des/Itgb6tm1Des,Tg(SFTPC-ITGB6)1Des/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0002945 abnormal inhibitory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0003216 absence seizures "impairment of consciousness without convulsions associated with widespread bilaterally synchronous spike-and-wave discharges (SWDs) in the electroencephalogram (EEG)" [RGD:Rat Genome Database submission]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: D2.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acetm2Unc/Acetm2Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0004000 impaired passive avoidance behavior "decrease in or absence of the latency of an animal to enter an hostile environment where it receives a unpleasant or punishing stimuli applied previously" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Hrh2tm1Yfks/Hrh2tm1Yfks
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004008 abnormal GABA receptor currents "change in the measured amplitude or duration of response to stimulation of GABA receptors" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008414 abnormal spatial reference memory "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Itgb6tm1Des/Itgb6tm1Des,Tg(SFTPC-ITGB6)1Des/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0008840 abnormal spike wave discharge "anomaly in the characteristic epileptiformic electroencephalographic (EEG) activity detected in generalized absence epilepsy" [PMID:16725200]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: D2.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Gabra1tm1.1Uru/Gabra1tm1.1Uru
Genetic Background: either: 129X1.129P2-Gabra1tm1.1Uru or B6.129P2-Gabra1tm1.1Uru

 MP:0008874 decreased sensitivity to xenobiotics "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Cacna1gtm1Hssh/Cacna1gtm1Hssh,Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

 MP:0009435 abnormal miniature inhibitory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm1.1Geh/Gabra1+
Genetic Background: B6.129(Cg)-Gabra1tm1.1Geh

Allelic Composition: Gabra1tm1.1Mjga/Gabra1+
Genetic Background: B6J.Cg-Gabra1tm1.1Mjga

 MP:0009538 abnormal synapse morphology "any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]
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Allelic Composition: Gabrg2tm1.1(Gabrg2)Wwis/Gabrg2tm1.1(Gabrg2)Wwis
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009745 abnormal behavioral response to xenobiotic "any anomaly in the behavioral response induced by a foreign compound, such as consumption preference, induced hyperactivity or stereotypic behavior" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm1Geh/Gabra1tm1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0009747 impaired behavioral response to xenobiotic "decreased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm1.1Uru/Gabra1tm1.1Uru
Genetic Background: either: 129X1.129P2-Gabra1tm1.1Uru or B6.129P2-Gabra1tm1.1Uru

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Gabra1tm2.1Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Gabra1tm1Twr/Gabra1tm1Twr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ryr2tm2.1Maya/Ryr2+
Genetic Background: involves: C57BL/6J

Allelic Composition: Gabra1tm1.1Geh/Gabra1tm1.1Geh
Genetic Background: D2.129(Cg)-Gabra1tm1.1Geh

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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