ENSMUSG00000015599


Mus musculus

Features
Gene ID: ENSMUSG00000015599
  
Biological name :Ttbk1
  
Synonyms : Q6PCN3 / tau tubulin kinase 1 / Ttbk1
  
Possible biological names infered from orthology : Q5TCY1
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: C
Gene start: 46442448
Gene end: 46487675
  
Corresponding Affymetrix probe sets: 10451303 (MoGene1.0st)   1443528_at (Mouse Genome 430 2.0 Array)   1445479_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044580
Ensembl peptide - ENSMUSP00000153583
Ensembl peptide - ENSMUSP00000153386
NCBI entrez gene - 106763     See in Manteia.
MGI - MGI:2147036
RefSeq - NM_001162864
RefSeq - XM_006523445
RefSeq Peptide - NP_001156336
swissprot - A0A286YE90
swissprot - Q6PCN3
swissprot - A0A286YDE4
Ensembl - ENSMUSG00000015599
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttbk1aENSDARG00000056019Danio rerio
 ttbk1bENSDARG00000056659Danio rerio
 TTBK1ENSGALG00000008627Gallus gallus
 TTBK1ENSG00000146216Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ttbk2 / Q3UVR3 / tau tubulin kinase 2 / Q6IQ55*ENSMUSG0000009010038
Csnk1d / Q9DC28 / casein kinase 1, delta / P48730*ENSMUSG0000002516210
Csnk1e / Q9JMK2 / Casein kinase I isoform epsilon / P49674* / Z98749.3* / casein kinase 1 epsilon*ENSMUSG000000224339
Q8BK63 / Csnk1a1 / casein kinase 1, alpha 1 / P48729*ENSMUSG000000245768


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032273 positive regulation of protein polymerization IEA
 biological_processGO:0061890 positive regulation of astrocyte activation IEA
 biological_processGO:1903980 positive regulation of microglial cell activation IEA
 biological_processGO:1904031 positive regulation of cyclin-dependent protein kinase activity IEA
 biological_processGO:2001056 positive regulation of cysteine-type endopeptidase activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0045298 tubulin complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr