ENSMUSG00000018666


Mus musculus

Features
Gene ID: ENSMUSG00000018666
  
Biological name :Cbx1
  
Synonyms : Cbx1 / Chromobox protein homolog 1 / P83917
  
Possible biological names infered from orthology : chromobox 1 / P83916
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 96789127
Gene end: 96808640
  
Corresponding Affymetrix probe sets: 10380689 (MoGene1.0st)   1422935_x_at (Mouse Genome 430 2.0 Array)   1431773_at (Mouse Genome 430 2.0 Array)   1433718_a_at (Mouse Genome 430 2.0 Array)   1436266_x_at (Mouse Genome 430 2.0 Array)   1450797_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000018810
Ensembl peptide - ENSMUSP00000078640
Ensembl peptide - ENSMUSP00000091475
Ensembl peptide - ENSMUSP00000137834
NCBI entrez gene - 12412     See in Manteia.
MGI - MGI:105369
RefSeq - XM_017314242
RefSeq - NM_007622
RefSeq - XM_006532099
RefSeq - XM_006532100
RefSeq - XM_006532102
RefSeq - XM_011248704
RefSeq Peptide - NP_031648
swissprot - P83917
swissprot - Q7TPM0
swissprot - Q9CYJ8
Ensembl - ENSMUSG00000018666
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbx1aENSDARG00000004189Danio rerio
 cbx1bENSDARG00000054442Danio rerio
 CBX1ENSGALG00000033926Gallus gallus
 CBX1ENSG00000108468Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cbx3 / chromobox protein homolog 3 / Q13185* / chromobox 3*ENSMUSG0000002983671
Cbx5 / Q61686 / Mus musculus chromobox 5 (Cbx5), transcript variant 4, mRNA. / P45973* / chromobox 5*ENSMUSG0000000957564


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR008251  Chromo shadow domain
 IPR016197  Chromo-like domain superfamily
 IPR017984  Chromo domain subgroup
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0001939 female pronucleus IDA
 cellular_componentGO:0001940 male pronucleus IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005721 pericentric heterochromatin IDA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0010369 chromocenter IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:1990226 histone methyltransferase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hprtb-m3/Y,Impdh2tm1Bmi/Impdh2+
Genetic Background: involves: 129P2/OlaHsd

 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Grhl3tm1Jane/Grhl3+,Ptentm1Mak/Pten+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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