ENSMUSG00000019990


Mus musculus

Features
Gene ID: ENSMUSG00000019990
  
Biological name :Pde7b
  
Synonyms : cAMP-specific 3,5-cyclic phosphodiesterase 7B / Pde7b / Q9QXQ1
  
Possible biological names infered from orthology : phosphodiesterase 7B / Q9NP56
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: A3
Gene start: 20398004
Gene end: 20725078
  
Corresponding Affymetrix probe sets: 10368175 (MoGene1.0st)   1421353_at (Mouse Genome 430 2.0 Array)   1450213_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020165
Ensembl peptide - ENSMUSP00000132378
Ensembl peptide - ENSMUSP00000130596
Ensembl peptide - ENSMUSP00000126913
Ensembl peptide - ENSMUSP00000126324
NCBI entrez gene - 29863     See in Manteia.
MGI - MGI:1352752
RefSeq - XM_006512758
RefSeq - NM_013875
RefSeq Peptide - NP_001334295
RefSeq Peptide - NP_038903
swissprot - E9Q5I0
swissprot - E9PW23
swissprot - E9PZN2
swissprot - Q9QXQ1
swissprot - E9Q0W7
Ensembl - ENSMUSG00000019990
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE7BENSGALG00000013941Gallus gallus
 PDE7BENSG00000171408Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pde7a / P70453 / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A / Q13946* / phosphodiesterase 7A*ENSMUSG0000006909455
Pde4a / O89084 / phosphodiesterase 4A, cAMP specific / P27815* / phosphodiesterase 4A*ENSMUSG0000003217730
Pde4d / Q01063 / cAMP-specific 3,5-cyclic phosphodiesterase 4D / Q08499* / phosphodiesterase 4D*ENSMUSG0000002169930
Pde4b / phosphodiesterase 4B, cAMP specific / Q07343* / phosphodiesterase 4B*ENSMUSG0000002852528
Pde4c / Q3UEI1 / cAMP-specific 3,5-cyclic phosphodiesterase 4C / Q08493* / AC008397.2* / phosphodiesterase 4C*ENSMUSG0000003184227
Pde8a / O88502 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A / O60658* / phosphodiesterase 8A*ENSMUSG0000002558424
Pde1c / Q64338 / phosphodiesterase 1C / Q14123*ENSMUSG0000000434723
Pde8b / E9Q4S1 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B / O95263* / AC022414.1* / phosphodiesterase 8B* / high affinity cAMP-specific and IBMX-ins...ENSMUSG0000002168422
Pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSMUSG0000005917322
Pde1b / Q01065 / Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B / Q01064* / phosphodiesterase 1B*ENSMUSG0000002248922


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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