ENSMUSG00000031842


Mus musculus

Features
Gene ID: ENSMUSG00000031842
  
Biological name :Pde4c
  
Synonyms : cAMP-specific 3,5-cyclic phosphodiesterase 4C / Pde4c / Q3UEI1
  
Possible biological names infered from orthology : AC008397.2 / phosphodiesterase 4C / Q08493
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 70723720
Gene end: 70751186
  
Corresponding Affymetrix probe sets: 10572466 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000153213
Ensembl peptide - ENSMUSP00000034307
Ensembl peptide - ENSMUSP00000105722
Ensembl peptide - ENSMUSP00000119312
NCBI entrez gene - 110385     See in Manteia.
MGI - MGI:99556
RefSeq - XM_011242260
RefSeq - NM_001310465
RefSeq - NM_201607
RefSeq - XM_011242248
RefSeq - XM_011242258
RefSeq - XM_011242259
RefSeq Peptide - NP_001297394
RefSeq Peptide - NP_963901
swissprot - D3Z2G1
swissprot - Q3UEI1
swissprot - A0A286YD02
Ensembl - ENSMUSG00000031842
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde4caENSDARG00000013221Danio rerio
 pde4cbENSDARG00000002411Danio rerio
 ENSGALG00000037029Gallus gallus
 PDE4CENSG00000105650Homo sapiens
 Q08493ENSG00000285188Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pde4d / Q01063 / cAMP-specific 3,5-cyclic phosphodiesterase 4D / Q08499* / phosphodiesterase 4D*ENSMUSG0000002169962
Pde4a / O89084 / phosphodiesterase 4A, cAMP specific / P27815* / phosphodiesterase 4A*ENSMUSG0000003217762
Pde4b / phosphodiesterase 4B, cAMP specific / Q07343* / phosphodiesterase 4B*ENSMUSG0000002852560
Pde1c / Q64338 / phosphodiesterase 1C / Q14123*ENSMUSG0000000434723
Pde8a / O88502 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A / O60658* / phosphodiesterase 8A*ENSMUSG0000002558422
Pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSMUSG0000005917322
Pde1b / Q01065 / Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B / Q01064* / phosphodiesterase 1B*ENSMUSG0000002248922
Pde8b / E9Q4S1 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B / O95263* / AC022414.1* / phosphodiesterase 8B* / high affinity cAMP-specific and IBMX-ins...ENSMUSG0000002168421
Pde7a / P70453 / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A / Q13946* / phosphodiesterase 7A*ENSMUSG0000006909420
Pde7b / Q9QXQ1 / cAMP-specific 3,5-cyclic phosphodiesterase 7B / Q9NP56* / phosphodiesterase 7B*ENSMUSG0000001999019


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
DARPP-32 events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr