Manteia

ENSMUSG00000020230

Mus musculus

Features

Gene ID:	ENSMUSG00000020230

Biological name :	Prmt2

Synonyms :	Prmt2 / protein arginine N-methyltransferase 2

Possible biological names infered from orthology :	P55345 / protein arginine methyltransferase 2

Species:	Mus musculus

Chr. number:	10
Strand:	-1
Band:	C1
Gene start:	76207222
Gene end:	76237865

Corresponding Affymetrix probe sets:	10370072 (MoGene1.0st) 1416844_at (Mouse Genome 430 2.0 Array) 1437234_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000097166 Ensembl peptide - ENSMUSP00000137725 Ensembl peptide - ENSMUSP00000020452 Ensembl peptide - ENSMUSP00000151456 Ensembl peptide - ENSMUSP00000097167 Ensembl peptide - ENSMUSP00000137707 NCBI entrez gene - 15468 See in Manteia. MGI - MGI:1316652 RefSeq - NM_001077638 RefSeq - NM_001302965 RefSeq - NM_133182 RefSeq Peptide - NP_001289894 RefSeq Peptide - NP_573445 RefSeq Peptide - NP_001071106 swissprot - Q3UKX1 swissprot - A0A1W2P6Z3 swissprot - Q3UID4 swissprot - M0QW88 Ensembl - ENSMUSG00000020230

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Carm1 / Q9WVG6 / Histone-arginine methyltransferase CARM1 / Q86X55* / coactivator associated arginine methyltransferase 1*	ENSMUSG00000032185	27
Prmt3 / Q922H1 / protein arginine N-methyltransferase 3 / O60678* / protein arginine methyltransferase 3*	ENSMUSG00000030505	27
Prmt6 / Q6NZB1 / protein arginine N-methyltransferase 6 / Q96LA8* / protein arginine methyltransferase 6*	ENSMUSG00000049300	27
Prmt8 / Q6PAK3 / protein arginine N-methyltransferase 8 / Q9NR22* / protein arginine methyltransferase 8*	ENSMUSG00000030350	25
Prmt1 / Q9JIF0 / protein arginine N-methyltransferase 1 / Q99873* / protein arginine methyltransferase 1*	ENSMUSG00000109324	24

Protein motifs (from Interpro)

Interpro ID	Name
IPR001452	SH3 domain
IPR007848	Methyltransferase small domain
IPR025799	Protein arginine N-methyltransferase
IPR029063	S-adenosyl-L-methionine-dependent methyltransferase
IPR036028	SH3-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006479	protein methylation	IEA
biological_process	GO:0016571	histone methylation	IEA
biological_process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IEA
biological_process	GO:0032259	methylation	IEA
biological_process	GO:0043065	positive regulation of apoptotic process	IEA
biological_process	GO:0045892	negative regulation of transcription, DNA-templated	IEA
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IEA
biological_process	GO:0060765	regulation of androgen receptor signaling pathway	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0003713	transcription coactivator activity	IEA
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0008168	methyltransferase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0030331	estrogen receptor binding	IEA
molecular_function	GO:0033142	progesterone receptor binding	IEA
molecular_function	GO:0042054	histone methyltransferase activity	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA
molecular_function	GO:0042974	retinoic acid receptor binding	IEA
molecular_function	GO:0042975	peroxisome proliferator activated receptor binding	IEA
molecular_function	GO:0046966	thyroid hormone receptor binding	IEA
molecular_function	GO:0050681	androgen receptor binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0003077	abnormal cell cycle	"failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]	Show Allelic Composition: Cdk4^tm1Kiyo/Cdk4⁺,Lin9^tm1Orc/Lin9⁺ Genetic Background: involves: 129S1/Sv
MP:0004883	abnormal blood vessel healing	"anomaly in the repair process of blood vessels after injury" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cdk4^tm1Kiyo/Cdk4⁺,Lin9^tm1Orc/Lin9⁺ Genetic Background: involves: 129S1/Sv
MP:0010101	increased sacral vertebrae number	"increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prkab1^{tm1a(KOMP)Wtsi}/Prkab1^{tm1a(KOMP)Wtsi} Genetic Background: C57BL/6N-Prkab1^{tm1a(KOMP)Wtsi}/Wtsi

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr