ENSMUSG00000021846


Mus musculus

Features
Gene ID: ENSMUSG00000021846
  
Biological name :Peli2
  
Synonyms : Peli2 / pellino E3 ubiquitin protein ligase family member 2
  
Possible biological names infered from orthology : Q9HAT8
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 48120823
Gene end: 48281575
  
Corresponding Affymetrix probe sets: 10414417 (MoGene1.0st)   10414427 (MoGene1.0st)   1419006_s_at (Mouse Genome 430 2.0 Array)   1436966_at (Mouse Genome 430 2.0 Array)   1437181_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154661
Ensembl peptide - ENSMUSP00000072894
Ensembl peptide - ENSMUSP00000154335
Ensembl peptide - ENSMUSP00000154648
NCBI entrez gene - 93834     See in Manteia.
MGI - MGI:1891445
RefSeq - XM_006519740
RefSeq - NM_033602
RefSeq - XM_006519742
RefSeq - XM_011245231
RefSeq - XM_006519741
RefSeq Peptide - NP_291080
swissprot - E9QPQ6
Ensembl - ENSMUSG00000021846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PELI2ENSGALG00000012124Gallus gallus
 PELI2ENSG00000139946Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Peli1 / Q8C669 / pellino 1 / Q96FA3* / pellino E3 ubiquitin protein ligase 1*ENSMUSG0000002013479
Peli3 / E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 / Q8N2H9* / pellino E3 ubiquitin protein ligase family member 3*ENSMUSG0000002490170


Protein motifs (from Interpro)
Interpro ID Name
 IPR006800  Pellino family
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0008063 Toll signaling pathway IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 signaling
IRAK1 recruits IKK complex
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031392 Irak1 / Q62406 / Interleukin-1 receptor-associated kinase 1 / P51617*  / reaction / complex
 ENSMUSG00000021846 Peli2 / pellino E3 ubiquitin protein ligase family member 2 / Q9HAT8*  / reaction
 ENSMUSG00000027164 Traf6 / P70196 / TNF receptor-associated factor 6 / Q9Y4K3*  / complex / reaction
 ENSMUSG00000059883 Irak4 / Q8R4K2 / Interleukin-1 receptor-associated kinase 4 / Q9NWZ3*  / complex / reaction
 ENSMUSG00000024901 Peli3 / E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 / Q8N2H9* / pellino E3 ubiquitin protein ligase family member 3*  / reaction
 ENSMUSG00000020134 Peli1 / Q8C669 / pellino 1 / Q96FA3* / pellino E3 ubiquitin protein ligase 1*  / reaction






 

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