ENSMUSG00000022091


Mus musculus

Features
Gene ID: ENSMUSG00000022091
  
Biological name :Sorbs3
  
Synonyms : Q9R1Z8 / sorbin and SH3 domain containing 3 / Sorbs3
  
Possible biological names infered from orthology : O60504
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D2
Gene start: 70180468
Gene end: 70211989
  
Corresponding Affymetrix probe sets: 10421269 (MoGene1.0st)   1419329_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022682
Ensembl peptide - ENSMUSP00000153715
Ensembl peptide - ENSMUSP00000154195
Ensembl peptide - ENSMUSP00000154773
NCBI entrez gene - 20410     See in Manteia.
MGI - MGI:700013
RefSeq - XM_017315934
RefSeq - NM_001271407
RefSeq - NM_001271408
RefSeq - NM_011366
RefSeq - XM_006518736
RefSeq - XM_006518737
RefSeq - XM_006518739
RefSeq - XM_006518741
RefSeq - XM_017315933
RefSeq Peptide - NP_001258337
RefSeq Peptide - NP_035496
RefSeq Peptide - NP_001258336
swissprot - Q8K0M3
swissprot - Q9R1Z8
Ensembl - ENSMUSG00000022091
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sorbs3ENSDARG00000037476Danio rerio
 O60504ENSG00000120896Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sorbs1 / sorbin and SH3 domain containing 1 / Q9BX66*ENSMUSG0000002500632
Q3UTJ2 / Sorbs2 / sorbin and SH3 domain containing 2 / O94875*ENSMUSG0000003162626
Q8C120 / Sh3rf3 / SH3 domain-containing RING finger protein 3 / Q8TEJ3* / SH3 domain containing ring finger 3*ENSMUSG0000003799015
Sh3rf1 / SH3 domain containing ring finger 1 / Q7Z6J0*ENSMUSG0000003164215
Q91X43 / Sh3d19 / SH3 domain-containing protein 19 / Q5HYK7* / SH3 domain containing 19*ENSMUSG0000002808213
Q8BZT2 / Sh3rf2 / Putative E3 ubiquitin-protein ligase SH3RF2 / Q8TEC5* / SH3 domain containing ring finger 2*ENSMUSG0000005771911


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR003127  SoHo domain
 IPR028510  Vinexin
 IPR035607  Vinexin, SH3 domain 3
 IPR035608  Vinexin, SH3 domain 2
 IPR035609  Vinexin, SH3 domain 1
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0031589 cell-substrate adhesion IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0017166 vinculin binding IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002908 delayed wound healing "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037]
Show

Allelic Composition: Bmp5se-4CHLd/Bmp5se-4CHLd
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0003091 abnormal cell migration "defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Bmp5se-4CHLd/Bmp5se-4CHLd
Genetic Background: involves: 101/Rl * C3H/Rl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr