ENSMUSG00000031642


Mus musculus

Features
Gene ID: ENSMUSG00000031642
  
Biological name :Sh3rf1
  
Synonyms : SH3 domain containing ring finger 1 / Sh3rf1
  
Possible biological names infered from orthology : Q7Z6J0
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.1
Gene start: 61223872
Gene end: 61396071
  
Corresponding Affymetrix probe sets: 10571958 (MoGene1.0st)   1421270_at (Mouse Genome 430 2.0 Array)   1421271_at (Mouse Genome 430 2.0 Array)   1442402_at (Mouse Genome 430 2.0 Array)   1445178_at (Mouse Genome 430 2.0 Array)   1455149_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034060
Ensembl peptide - ENSMUSP00000148118
NCBI entrez gene - 59009     See in Manteia.
MGI - MGI:1913066
RefSeq - NM_021506
RefSeq - XM_011242231
RefSeq Peptide - NP_067481
swissprot - E9QQ33
swissprot - A0A1B0GSY0
Ensembl - ENSMUSG00000031642
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3rf1ENSDARG00000070470Danio rerio
 SH3RF1ENSGALG00000009692Gallus gallus
 Q7Z6J0ENSG00000154447Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C120 / Sh3rf3 / SH3 domain-containing RING finger protein 3 / Q8TEJ3* / SH3 domain containing ring finger 3*ENSMUSG0000003799047
Q8BZT2 / Sh3rf2 / Putative E3 ubiquitin-protein ligase SH3RF2 / Q8TEC5* / SH3 domain containing ring finger 2*ENSMUSG0000005771927
Q3UTJ2 / Sorbs2 / sorbin and SH3 domain containing 2 / O94875*ENSMUSG0000003162612
Q9R1Z8 / Sorbs3 / sorbin and SH3 domain containing 3 / O60504*ENSMUSG0000002209112
Sorbs1 / sorbin and SH3 domain containing 1 / Q9BX66*ENSMUSG0000002500610
Q91X43 / Sh3d19 / SH3 domain-containing protein 19 / Q5HYK7* / SH3 domain containing 19*ENSMUSG000000280829


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR028502  E3 ubiquitin-protein ligase SH3RF1
 IPR035795  E3 ubiquitin-protein ligase SH3RF1, second SH3 domain
 IPR035816  SH3RF1/SH3RF3, fourth SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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