Manteia

ENSMUSG00000022332

Mus musculus

Features

Gene ID:	ENSMUSG00000022332

Biological name :	Khdrbs3

Synonyms :	KH domain-containing, RNA-binding, signal transduction-associated protein 3 / Khdrbs3 / Q9R226

Possible biological names infered from orthology :	KH RNA binding domain containing, signal transduction associated 3 / O75525

Species:	Mus musculus

Chr. number:	15
Strand:	1
Band:	D3
Gene start:	68928420
Gene end:	69101211

Corresponding Affymetrix probe sets:	10424559 (MoGene1.0st) 1453317_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000155218 Ensembl peptide - ENSMUSP00000022954 Ensembl peptide - ENSMUSP00000154871 Ensembl peptide - ENSMUSP00000154887 Ensembl peptide - ENSMUSP00000155136 NCBI entrez gene - 13992 See in Manteia. MGI - MGI:1313312 RefSeq - NM_010158 RefSeq - XM_006520410 RefSeq Peptide - NP_034288 swissprot - Q9R226 Ensembl - ENSMUSG00000022332

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9WU01 / Khdrbs2 / KH domain-containing, RNA-binding, signal transduction-associated protein 2 / Q5VWX1* / KH RNA binding domain containing, signal transduction associated 2*	ENSMUSG00000026058	65
Q60749 / Khdrbs1 / KH domain-containing, RNA-binding, signal transduction-associated protein 1 / Q07666* / KH RNA binding domain containing, signal transduction associated 1*	ENSMUSG00000028790	57
Qk / Q9QYS9 / Protein quaking / QKI* / Q96PU8* / QKI, KH domain containing RNA binding*	ENSMUSG00000062078	31
Sf1 / Q64213 / Splicing factor 1 / Q15637*	ENSMUSG00000024949	27

Protein motifs (from Interpro)

Interpro ID	Name
IPR004087	K Homology domain
IPR004088	K Homology domain, type 1
IPR032335	Sam68, tyrosine-rich domain
IPR032571	KHDRBS, Qua1 domain
IPR036612	K Homology domain, type 1 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006397	mRNA processing	IEA
biological_process	GO:0048024	regulation of mRNA splicing, via spliceosome	IDA
biological_process	GO:0051259	protein complex oligomerization	IEA
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005654	nucleoplasm	IEA
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0003723	RNA binding	IEA
molecular_function	GO:0017124	SH3 domain binding	IEA
molecular_function	GO:0019904	protein domain specific binding	IEA
molecular_function	GO:0042802	identical protein binding	IEA

Pathways (from Reactome)

Pathway description

PTK6 Regulates Proteins Involved in RNA Processing

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Kdm8^{tm1b(EUCOMM)Wtsi}/Kdm8^{tm1b(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Kdm8^{tm1b(EUCOMM)Wtsi}/Ics
MP:0001935	reduced litter size	"fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Scn3a^tm1.2Jwo/Scn3a^tm1.2Jwo Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * BALB/c * C57BL/6

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000038751	Ptk6 / Q64434 / PTK6 protein tyrosine kinase 6 / Q13882* / protein tyrosine kinase 6*	/ reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr