ENSMUSG00000022462


Mus musculus

Features
Gene ID: ENSMUSG00000022462
  
Biological name :Slc38a2
  
Synonyms : Q8CFE6 / Slc38a2 / Sodium-coupled neutral amino acid transporter 2
  
Possible biological names infered from orthology : Q96QD8 / solute carrier family 38 member 2
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 96687392
Gene end: 96699730
  
Corresponding Affymetrix probe sets: 10431894 (MoGene1.0st)   1426722_at (Mouse Genome 430 2.0 Array)   1429593_at (Mouse Genome 430 2.0 Array)   1429594_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023099
NCBI entrez gene - 67760     See in Manteia.
MGI - MGI:1915010
RefSeq - NM_175121
RefSeq - XM_006521300
RefSeq Peptide - NP_780330
swissprot - Q8CFE6
Ensembl - ENSMUSG00000022462
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5SPB1ENSDARG00000045886Danio rerio
 SLC38A2ENSGALG00000008497Gallus gallus
 Q96QD8ENSG00000134294Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R1S9 / Slc38a4 / Mus musculus solute carrier family 38, member 4 (Slc38a4), transcript variant 1, mRNA. / Q969I6* / solute carrier family 38 member 4*ENSMUSG0000002246463
Q9DCP2 / Slc38a3 / Sodium-coupled neutral amino acid transporter 3 / Q99624* / solute carrier family 38 member 3*ENSMUSG0000001006452
Q8K2P7 / Slc38a1 / Sodium-coupled neutral amino acid transporter 1 / Q9H2H9* / solute carrier family 38 member 1*ENSMUSG0000002316949
Q3U1J0 / Slc38a5 / Sodium-coupled neutral amino acid transporter 5 / Q8WUX1* / solute carrier family 38 member 5*ENSMUSG0000003117048
G3UVW3 / Slc38a6 / Probable sodium-coupled neutral amino acid transporter 6 / Q8IZM9* / solute carrier family 38 member 6*ENSMUSG0000004471240
Q3USY0 / Slc38a11 / Putative sodium-coupled neutral amino acid transporter 11 / Q08AI6* / solute carrier family 38 member 11*ENSMUSG0000006117123
Q5I012 / Slc38a10 / Putative sodium-coupled neutral amino acid transporter 10 / Q9HBR0* / solute carrier family 38 member 10*ENSMUSG0000006130620


Protein motifs (from Interpro)
Interpro ID Name
 IPR013057  Amino acid transporter, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0006868 glutamine transport IDA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0031460 glycine betaine transport IEA
 biological_processGO:0032328 alanine transport IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0015171 amino acid transmembrane transporter activity IDA
 molecular_functionGO:0015186 L-glutamine transmembrane transporter activity IDA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000559 abnormal femur morphology "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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