MP:0000061 | fragile skeleton | "easily damaged or broken bones" [J:14208] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0000195 | hypocalcemia | "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Slc16a2tm1a(KOMP)Wtsi/Slc16a2tm1a(KOMP)Wtsi Genetic Background: B6JTyr;B6N-Slc16a2tm1a(KOMP)Wtsi/Wtsi
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MP:0000455 | abnormal maxilla morphology | "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Slc16a2tm1a(KOMP)Wtsi/Slc16a2tm1a(KOMP)Wtsi Genetic Background: B6JTyr;B6N-Slc16a2tm1a(KOMP)Wtsi/Wtsi
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MP:0000609 | abnormal liver physiology | "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
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MP:0002590 | increased mean corpuscular volume | "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0002599 | increased mean platelet volume | "increased content of platelet cells over the norm" [cml:Cathleen M. Lutz, Mouse Genome Informatics Curator] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0002834 | decreased heart weight | "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0002874 | decreased hemoglobin content | "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0002875 | decreased erythrocyte count | "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0002966 | decreased circulating alkaline phosphatase level | "reduced activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0003179 | decreased platelet count | "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0003795 | abnormal bone structure | |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0004889 | increased energy expenditure | "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0005289 | increased oxygen consumption | "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0005316 | abnormal response to tactile stimuli | "anomalous reflex action normally induced by touch or pain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0005419 | hypoalbuminemia | "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0005553 | increased circulating creatinine level | "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0005567 | decreased circulating total protein level | "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0005627 | increased circulating potassium level | "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0005634 | decreased circulating sodium level | "less than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0005641 | increased mean corpuscular hemoglobin concentration | "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0008045 | decreased NK cell number | "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0008805 | decreased circulating amylase level | "reduction in the concentration of a group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans in the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:D08.811.277.450.066, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0008810 | increased circulating iron level | "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: B6JTyr;B6N-Slc38a10tm1a(EUCOMM)Wtsi/Wtsi
Allelic Composition: Slc38a10tm1a(EUCOMM)Wtsi/Slc38a10tm1a(EUCOMM)Wtsi Genetic Background: involves: C57BL/6 * C57BL/6N
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