ENSMUSG00000022762


Mus musculus

Features
Gene ID: ENSMUSG00000022762
  
Biological name :Ncam2
  
Synonyms : Ncam2 / Neural cell adhesion molecule 2 / O35136
  
Possible biological names infered from orthology : O15394
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C3.3
Gene start: 81200697
Gene end: 81624285
  
Corresponding Affymetrix probe sets: 10436636 (MoGene1.0st)   1421592_at (Mouse Genome 430 2.0 Array)   1421593_at (Mouse Genome 430 2.0 Array)   1425301_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049390
Ensembl peptide - ENSMUSP00000063468
NCBI entrez gene - 17968     See in Manteia.
MGI - MGI:97282
RefSeq - NM_001113208
RefSeq - NM_010954
RefSeq Peptide - NP_001106679
RefSeq Peptide - NP_035084
swissprot - O35136
Ensembl - ENSMUSG00000022762
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ncam2ENSDARG00000017466Danio rerio
 NCAM2ENSGALG00000015737Gallus gallus
 NCAM2ENSG00000154654Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ncam1 / neural cell adhesion molecule 1 isoform 3 / P13591* / neural cell adhesion molecule 1*ENSMUSG0000003954244
Robo2 / roundabout guidance receptor 2 / Q9HCK4*ENSMUSG0000005251622
Robo1 / roundabout guidance receptor 1 / Q9Y6N7*ENSMUSG0000002288322
Robo3 / roundabout guidance receptor 3 / Q96MS0*ENSMUSG0000003212821
Cdon / Q32MD9 / Cell adhesion molecule-related/down-regulated by oncos / Q4KMG0* / cell adhesion associated, oncogene regulated*ENSMUSG0000003811921
Boc / BOC cell adhesion associated, oncogene regulated / Q9BWV1*ENSMUSG0000002268718
Robo4 / roundabout guidance receptor 4 / Q8WZ75*ENSMUSG0000003212510


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR009138  Neural cell adhesion
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0007608 sensory perception of smell IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000819 abnormal olfactory bulb morphology "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]
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Allelic Composition: Htr2atm1Grch/Htr2atm2Grch,Slc6a4tm1(cre)Grch/Slc6a4+
Genetic Background: involves: 129S6/SvEvTac

 MP:0001983 abnormal olfactory system physiology "abnormal function of the system relating to smell " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Htr2atm1Grch/Htr2atm2Grch,Slc6a4tm1(cre)Grch/Slc6a4+
Genetic Background: involves: 129S6/SvEvTac

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0009967 abnormal neuron proliferation "any anomaly in the ability of a neuron to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ddr2tm1c(EUCOMM)Wtsi/Ddr2tm1c(EUCOMM)Wtsi,Tg(KRT14-cre)1Amc/0,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: C57BL/6 * C57BL/6N * CBA * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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