| MP:0000220 | increased monocyte count | "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Mthfrtm1Rzn/Mthfr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0000240 | extramedullary hematopoiesis | "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000255 | vasculature congestion | "obstruction of the normal flux of blood within the blood vessel network" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000448 | pointed snout | "nose tapers to a small tip, sharper angle than wild type " [J:18378] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000528 | delayed kidney development | "late onset of the induction and/or differentiation of the kidney" [J:18048] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
Show
Allelic Composition: Fcgr2btm1Ttk/Fcgr2btm1Ttk,Il17atm1Yiw/Il17atm1Yiw
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000603 | pale liver | "liver lacking normal coloration, often refers to bloodless condition" [J:18048] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000607 | abnormal hepatocyte morphology | "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0000652 | enlarged sebaceous gland | "increased size of the sebum secreting glands of the hair shaft" [J:30249] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001176 | abnormal lung development | "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001237 | enlarged spinous cells | "increased size of the cells of the spinous layer of the epidermis" [J:47225] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001242 | hyperkeratosis | "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001244 | thin dermal layer | "reduced thickness of the dermis" [J:65030] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001286 | abnormal eye development | "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001290 | delayed eyelid opening | "late average time for the first postnatal eye opening" [J:17792] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001613 | abnormal vasodilation | "anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0001716 | abnormal placental labyrinth | "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001860 | liver inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002111 | abnormal tail morphology | "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002182 | abnormal astrocyte morphology | "anomalous structure, number or compostion of one of the large neuroglia cells of nervous tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002656 | abnormal keratinocyte differentiation | "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002699 | abnormal vitreous body | "anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0002792 | abnormal retinal vascularization | "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0003070 | increased vascular permeability | "greater or faster ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0003333 | liver fibrosis | "invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0003674 | oxidative stress | "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0003719 | abnormal pericyte morphology | "malformation in the connective tissue cells that occurs around capillaries or other small blood vessels " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0003743 | abnormal facial morphology | "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0003887 | increased hepatocyte apoptosis | "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0004003 | abnormal vascular endothelial cell physiology | "anomaly in the function of the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0004014 | abnormal uterine environment | "anomaly or inability of the uterus to support embryonic development" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0004125 | abnormal venule morphology | "any structural anomaly in the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0004126 | thin hypodermis | "reduced thickness of the innermost and thickest layer of the skin composed of loose connective tissue containing adipoctyes" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0004256 | abnormal maternal decidual layer morphology | "anomaly in the structure of the maternal uterine-derived portion of the placenta" [PMID:11433360] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0004903 | abnormal uterus weight | "anomaly in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0004921 | decreased placenta weight | "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0005186 | increased circulating progesterone level | "greater than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0005311 | abnormal circulating amino acid level | "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263] |
Show
Allelic Composition: Mthfrtm1Rzn/Mthfr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Allelic Composition: Cbstm1Unc/Cbstm1Unc
Genetic Background: B6.129P2-Cbstm1Unc/J
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0005332 | abnormal amino acid level | "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mthfrtm1Rzn/Mthfr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0005339 | increased susceptibility to atherosclerosis | "more likely than the norm to develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0005547 | abnormal Muller cell morphology | "anomalous structure of the elongated neuroglial cells that traverse all the layers of the retina and that act as supporting elements" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0005607 | decreased bleeding time | "less than the normal duration of blood flow after skin puncture; indicative of platement and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0005639 | hemosiderosis | "condition in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the reticuloendothelial system, without demonstrable tissue damage" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0006076 | abnormal circulating homocysteine level | "aberrant concentration in the blood of this amino acid" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:NCBI request] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
Allelic Composition: Cbstm1Unc/Cbstm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS*I278T)1Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Allelic Composition: Cbstm1Unc/Cbstm1Unc
Genetic Background: B6.129P2-Cbstm1Unc/J
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0006190 | retinal ischemia | "abnormal incidence of or response to loss of circulation in the retina; may be induced or spontaneous" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0008553 | increased circulating tumor necrosis factor level | "greater amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
|
| MP:0008751 | abnormal interleukin level | "deviation from the normal levels of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0008752 | abnormal tumor necrosis factor level | "deviation from the normal levels of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [MESH:D12.644.276.374.500.800] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0008852 | retinal neovascularization | "formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina" [MESH:C11.768.725] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0008871 | abnormal ovarian follicle number | "abnormal numbers of spheroid cell aggregations in the ovary" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0008957 | abnormal placenta junctional zone morphology | "fetally derived placental region that separates the maternal uterine tissue from the placenta labyrinth" [PMID:16367805] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0009007 | short estrous cycle | "decrease in the length of the sexual cycle of female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0009012 | short diestrus | "decrease in the length of the diestrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0009018 | short estrus | "decrease in the length of the estrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0009020 | prolonged metestrus | "increase in the length of the metestrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0009392 | retinal gliosis | "increased proliferation of neuroglia in a damaged area of the retina that may lead to the formation of scar tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
|
| MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cbstm1Unc/Cbstm1Unc,Tg(CBS)11181Eri/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0009661 | abnormal pregnancy | "any anomaly in the process of maintaining a developing embryo or fetus within the female body from conception to birth" [ISBN:0198542771 "Rugh, Roberts, The Mouse: Its Reproduction and Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0010097 | abnormal retinal blood vessel morphology | "any structural anomaly of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
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| MP:0010098 | abnormal retinal blood vessel pattern | "anomaly in the systematic arrangement of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
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| MP:0010452 | retina microaneurysm | "focal dilation of arteriocapillary junctions in the retina" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Prlrtm1Cnp/Prlr+
Genetic Background: involves: 129P2/OlaHsd
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| MP:0012065 | increased astrocyte number | "increase in the number of the large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord" [CL:0000127, MGI:csmith] |
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Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
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| MP:0012335 | increased circulating homocysteine level | "greater amount in the blood of sulfur-containing alpha-amino acid found in the plasma; blood levels are regulated by folic acid, vitamin B6 and vitamin B12" [MGI:csmith] |
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Allelic Composition: Mthfrtm1Rzn/Mthfr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
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| MP:0013022 | increased Ly6C high monocyte number | "increase in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues" [MGI:Annie_Speak] |
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Allelic Composition: Mthfrtm1Rzn/Mthfr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Cbstm1Unc/Cbstm1Unc,Tg(Mt1-CBS)25Waku/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6
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| MP:0014179 | abnormal blood-retinal barrier function | "anomaly in the function of the part of the blood-ocular barrier that consists of cells that are joined tightly together to prevent certain substances from entering the tissue of the retina; the BRB consists of non-fenestrated capillaries of the retinal circulation and tight-junctions between retinal epithelial cells preventing passage of large molecules from choriocapillaris into the retina; the BRB barrier becomes more leaky in patients with diabetic retinopathy" [https://en.wikipedia.org/wiki/Blood%E2%80%93retinal_barrier] |
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Allelic Composition: Cbstm1Unc/Cbs+
Genetic Background: B6.129P2-Cbstm1Unc/J
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