ENSMUSG00000024327


Mus musculus

Features
Gene ID: ENSMUSG00000024327
  
Biological name :Slc39a7
  
Synonyms : Q31125 / Slc39a7 / solute carrier family 39 (zinc transporter), member 7
  
Possible biological names infered from orthology : Q92504 / solute carrier family 39 member 7
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 34028267
Gene end: 34031690
  
Corresponding Affymetrix probe sets: 10450116 (MoGene1.0st)   1416949_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130102
Ensembl peptide - ENSMUSP00000133146
Ensembl peptide - ENSMUSP00000025186
NCBI entrez gene - 14977     See in Manteia.
MGI - MGI:95909
RefSeq - NM_008202
RefSeq - NM_001077709
RefSeq Peptide - NP_001071177
RefSeq Peptide - NP_032228
swissprot - Q31125
swissprot - E9PV10
swissprot - A0A068BIT0
Ensembl - ENSMUSG00000024327
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc39a7ENSDARG00000104451Danio rerio
 Q92504ENSG00000112473Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BZH0 / Slc39a13 / solute carrier family 39 (metal ion transporter), member 13 / Q96H72* / solute carrier family 39 member 13*ENSMUSG0000000210528
Q6P5F6 / Slc39a10 / Zinc transporter ZIP10 / Q9ULF5* / solute carrier family 39 member 10*ENSMUSG0000002598626
Q78IQ7 / Slc39a4 / solute carrier family 39 (zinc transporter), member 4 / Q6P5W5* / solute carrier family 39 member 4*ENSMUSG0000006335425
Q8C145 / Slc39a6 / Zinc transporter ZIP6 / Q13433* / solute carrier family 39 member 6*ENSMUSG0000002427024
Q5FWH7 / Slc39a12 / Zinc transporter ZIP12 / Q504Y0* / solute carrier family 39 member 12*ENSMUSG0000003694923
Q9D856 / Slc39a5 / Zinc transporter ZIP5 / Q6ZMH5* / solute carrier family 39 member 5*ENSMUSG0000003987822
Q75N73 / Slc39a14 / solute carrier family 39 (zinc transporter), member 14 / Q15043* / solute carrier family 39 member 14*ENSMUSG0000002209420
Q91W10 / Slc39a8 / Zinc transporter ZIP8 / Q9C0K1* / solute carrier family 39 member 8*ENSMUSG0000005389719


Protein motifs (from Interpro)
Interpro ID Name
 IPR003689  Zinc/iron permease


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006829 zinc ion transport IEA
 biological_processGO:0006882 cellular zinc ion homeostasis IBA
 biological_processGO:0030001 metal ion transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071577 zinc ion transmembrane transport IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046873 metal ion transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Zinc influx into cells by the SLC39 gene family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001658 increased mortality induced by gamma-irradiation "greater sensitivity to doses of ionizing radiation" [J:51834]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0008882 abnormal enterocyte physiology "any functional anomaly of the epithelial cells that have an apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen" [CL:0000584, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0008883 abnormal enterocyte proliferation "anomaly in the ability of the enterocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0008885 increased enterocyte apoptosis "increase in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0010158 abnormal intestine development "abnormal formation of the digestive tube passing from the stomach to the anus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mstntm1Sjl/Mstn+
Genetic Background: B6N.129-Mstntm1Sjl

 MP:0013486 decreased Paneth cell number "fewer than normal numbers of the large secretory cells containing coarse granules found at the base of the crypts of Lieberkuhn in the small intestine" [MGI:Anna]
Show

Allelic Composition: Slc39a7tm1.1Tfk/Slc39a7tm1.1Tfk,Lgr5tm1(cre/ERT2)Cle/Lgr5+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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