ENSMUSG00000002105


Mus musculus

Features
Gene ID: ENSMUSG00000002105
  
Biological name :Slc39a13
  
Synonyms : Q8BZH0 / Slc39a13 / solute carrier family 39 (metal ion transporter), member 13
  
Possible biological names infered from orthology : Q96H72 / solute carrier family 39 member 13
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E1
Gene start: 91061791
Gene end: 91070417
  
Corresponding Affymetrix probe sets: 10484927 (MoGene1.0st)   1423926_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118308
Ensembl peptide - ENSMUSP00000073263
Ensembl peptide - ENSMUSP00000078892
Ensembl peptide - ENSMUSP00000107063
NCBI entrez gene - 68427     See in Manteia.
MGI - MGI:1915677
RefSeq - XM_017319238
RefSeq - XM_006500099
RefSeq - XM_006500100
RefSeq - XM_006500101
RefSeq - XM_006500102
RefSeq - XM_017319236
RefSeq - NM_001290765
RefSeq - NM_026721
RefSeq Peptide - NP_001277694
RefSeq Peptide - NP_080997
swissprot - B7ZCF3
swissprot - Q8BZH0
swissprot - B2RQ45
Ensembl - ENSMUSG00000002105
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc39a13ENSDARG00000000442Danio rerio
 Q5ZI20ENSGALG00000008122Gallus gallus
 Q96H72ENSG00000165915Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q31125 / Slc39a7 / solute carrier family 39 (zinc transporter), member 7 / Q92504* / solute carrier family 39 member 7*ENSMUSG0000002432736
Q78IQ7 / Slc39a4 / solute carrier family 39 (zinc transporter), member 4 / Q6P5W5* / solute carrier family 39 member 4*ENSMUSG0000006335427
Q9D856 / Slc39a5 / Zinc transporter ZIP5 / Q6ZMH5* / solute carrier family 39 member 5*ENSMUSG0000003987823
Q5FWH7 / Slc39a12 / Zinc transporter ZIP12 / Q504Y0* / solute carrier family 39 member 12*ENSMUSG0000003694922
Q75N73 / Slc39a14 / solute carrier family 39 (zinc transporter), member 14 / Q15043* / solute carrier family 39 member 14*ENSMUSG0000002209422
Q6P5F6 / Slc39a10 / Zinc transporter ZIP10 / Q9ULF5* / solute carrier family 39 member 10*ENSMUSG0000002598620
Q91W10 / Slc39a8 / Zinc transporter ZIP8 / Q9C0K1* / solute carrier family 39 member 8*ENSMUSG0000005389720
Q8C145 / Slc39a6 / Zinc transporter ZIP6 / Q13433* / solute carrier family 39 member 6*ENSMUSG0000002427019


Protein motifs (from Interpro)
Interpro ID Name
 IPR003689  Zinc/iron permease


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006829 zinc ion transport IEA
 biological_processGO:0006882 cellular zinc ion homeostasis IMP
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0030001 metal ion transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061448 connective tissue development IMP
 biological_processGO:0071577 zinc ion transmembrane transport IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IC
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046873 metal ion transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000120 malocclusion "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000126 brittle teeth "fragile and likely to break teeth" [J:61509]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000131 abnormal long bone epiphysis morphology "the head of a developing long bone that is separated from the shaft by the epiphyseal plate" [J:61509]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000132 thickened epiphysis "wider than normal part of the long bones that initially develops from a distinct ossification center than the shaft" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000133 abnormal long bone metaphysis morphology "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000135 reduced cortical bone thickness "thinner than normal superficial layer of compact bone " [J:61509]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000165 abnormal hypertrophic chondrocyte zone "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000454 abnormal jaw morphology "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001243 abnormal dermal layer morphology "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003662 abnormal proliferative zone "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003671 abnormal eyelid opening 
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003723 abnormal long bone morphology "malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004189 abnormal alveolar process "any structural anomaly of the thickened ridge of bone in the mandible and maxilla that holds the tooth sockets" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004540 small maxilla "reduced size of the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004592 small mandible "reduced size of the lower bony framework of the mouth where the inferior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005006 abnormal osteoblast function "anomalous function of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005358 abnormal incisor morphology "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005543 corneal thinning "decreased thickness of the cornea, the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0006198 enophthalmos "sinking or retraction of the eye back into the socket" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0006395 abnormal epiphyseal plate morphology "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0030494 abnormal molar root morphology "any structural anomaly of the part of a molar tooth that is implanted in the gum" [MGI:anna]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr