ENSMUSG00000025185


Mus musculus

Features
Gene ID: ENSMUSG00000025185
  
Biological name :Loxl4
  
Synonyms : Loxl4 / Lysyl oxidase homolog 4 / Q924C6
  
Possible biological names infered from orthology : lysyl oxidase like 4 / Q96JB6
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 42593982
Gene end: 42612813
  
Corresponding Affymetrix probe sets: 10467768 (MoGene1.0st)   1421153_at (Mouse Genome 430 2.0 Array)   1450134_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125803
Ensembl peptide - ENSMUSP00000126686
Ensembl peptide - ENSMUSP00000126552
Ensembl peptide - ENSMUSP00000026190
NCBI entrez gene - 67573     See in Manteia.
MGI - MGI:1914823
RefSeq - NM_001164311
RefSeq - NM_053083
RefSeq Peptide - NP_001157783
RefSeq Peptide - NP_444313
swissprot - Q924C6
swissprot - E9PY86
swissprot - E9Q600
Ensembl - ENSMUSG00000025185
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LOXL4ENSGALG00000013090Gallus gallus
 LOXL4ENSG00000138131Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Loxl3 / Q9Z175 / Lysyl oxidase homolog 3 / P58215* / lysyl oxidase like 3*ENSMUSG0000000069354
Loxl2 / P58022 / Lysyl oxidase homolog 2 / Q9Y4K0* / lysyl oxidase like 2*ENSMUSG0000003420554
Loxl1 / lysyl oxidase like 1 / Q08397*ENSMUSG0000003233422
Lox / P28301 / Protein-lysine 6-oxidase / P28300* / lysyl oxidase*ENSMUSG0000002452918
Cd6 / Q61003 / T-cell differentiation antigen CD6 / P30203* / CD6 molecule*ENSMUSG0000002467018
Msr1 / P30204 / Macrophage scavenger receptor types I and II / P21757* / macrophage scavenger receptor 1*ENSMUSG0000002504410
Q8K299 / Scara5 / Scavenger receptor class A member 5 / Q6ZMJ2*ENSMUSG0000002203210
Marco / Q60754 / Macrophage receptor MARCO / Q9UEW3* / macrophage receptor with collagenous structure*ENSMUSG0000002639010


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001695  Lysyl oxidase
 IPR013783  Immunoglobulin-like fold
 IPR017448  SRCR-like domain
 IPR019828  Lysyl oxidase, conserved site
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0004720 protein-lysine 6-oxidase activity IDA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Elastic fibre formation
Crosslinking of collagen fibrils


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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