ENSG00000138131


Homo sapiens

Features
Gene ID: ENSG00000138131
  
Biological name :LOXL4
  
Synonyms : LOXL4 / lysyl oxidase like 4 / Q96JB6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q24.2
Gene start: 98247690
Gene end: 98268250
  
Corresponding Affymetrix probe sets: 227145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260702
NCBI entrez gene - 84171     See in Manteia.
OMIM - 607318
RefSeq - XM_006718020
RefSeq - NM_032211
RefSeq - XM_005270216
RefSeq Peptide - NP_115587
swissprot - Q96JB6
Ensembl - ENSG00000138131
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LOXL4ENSGALG00000013090Gallus gallus
 Loxl4ENSMUSG00000025185Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LOXL3 / P58215 / lysyl oxidase like 3ENSG0000011531855
LOXL2 / Q9Y4K0 / lysyl oxidase like 2ENSG0000013401354
LOXL1 / Q08397 / lysyl oxidase like 1ENSG0000012903821
CD6 / P30203 / CD6 moleculeENSG0000001372518
LOX / P28300 / lysyl oxidaseENSG0000011308318
MSR1 / P21757 / macrophage scavenger receptor 1ENSG0000003894510
MARCO / Q9UEW3 / macrophage receptor with collagenous structureENSG0000001916910
Q6ZMJ2 / SCARA5 / scavenger receptor class A member 5ENSG0000016807910


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001695  Lysyl oxidase
 IPR017448  SRCR-like domain
 IPR019828  Lysyl oxidase, conserved site
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Elastic fibre formation
Crosslinking of collagen fibrils


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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