ENSG00000013725


Homo sapiens

Features
Gene ID: ENSG00000013725
  
Biological name :CD6
  
Synonyms : CD6 / CD6 molecule / P30203
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.2
Gene start: 60971680
Gene end: 61020377
  
Corresponding Affymetrix probe sets: 1566099_at (Human Genome U133 Plus 2.0 Array)   1566447_at (Human Genome U133 Plus 2.0 Array)   1566448_at (Human Genome U133 Plus 2.0 Array)   208602_x_at (Human Genome U133 Plus 2.0 Array)   211893_x_at (Human Genome U133 Plus 2.0 Array)   211900_x_at (Human Genome U133 Plus 2.0 Array)   213958_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443747
Ensembl peptide - ENSP00000440055
Ensembl peptide - ENSP00000443748
Ensembl peptide - ENSP00000323280
Ensembl peptide - ENSP00000340334
Ensembl peptide - ENSP00000340628
Ensembl peptide - ENSP00000390676
Ensembl peptide - ENSP00000410638
NCBI entrez gene - 923     See in Manteia.
OMIM - 186720
RefSeq - XM_011545362
RefSeq - NM_001254750
RefSeq - NM_001254751
RefSeq - NM_006725
RefSeq - XM_006718738
RefSeq - XM_006718739
RefSeq - XM_006718740
RefSeq - XM_006718741
RefSeq - XM_011545360
RefSeq Peptide - NP_001241680
RefSeq Peptide - NP_006716
RefSeq Peptide - NP_001241679
swissprot - G5E973
swissprot - H0YGL3
swissprot - E7ER04
swissprot - P30203
swissprot - F5H835
swissprot - F6UFK6
Ensembl - ENSG00000013725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-242e21.3ENSDARG00000075723Danio rerio
 CD6ENSGALG00000043016Gallus gallus
 Cd6ENSMUSG00000024670Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LOXL4 / Q96JB6 / lysyl oxidase like 4ENSG0000013813121
LOXL2 / Q9Y4K0 / lysyl oxidase like 2ENSG0000013401321
LOXL3 / P58215 / lysyl oxidase like 3ENSG0000011531820
Q6ZMJ2 / SCARA5 / scavenger receptor class A member 5ENSG000001680799
MARCO / Q9UEW3 / macrophage receptor with collagenous structureENSG000000191699
MSR1 / P21757 / macrophage scavenger receptor 1ENSG000000389459
LOXL1 / Q08397 / lysyl oxidase like 1ENSG000001290388
LOX / P28300 / lysyl oxidaseENSG000001130836


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR017448  SRCR-like domain
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001771 immunological synapse formation IMP
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002438 acute inflammatory response to antigenic stimulus IDA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0032496 response to lipopolysaccharide IDA
 biological_processGO:0042102 positive regulation of T cell proliferation IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:1900017 positive regulation of cytokine production involved in inflammatory response IDA
 cellular_componentGO:0001772 immunological synapse IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0042101 T cell receptor complex IDA
 molecular_functionGO:0001530 lipopolysaccharide binding IDA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0070891 lipoteichoic acid binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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