ENSG00000168079


Homo sapiens

Features
Gene ID: ENSG00000168079
  
Biological name :SCARA5
  
Synonyms : Q6ZMJ2 / SCARA5 / scavenger receptor class A member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p21.1
Gene start: 27869882
Gene end: 27992727
  
Corresponding Affymetrix probe sets: 1554705_at (Human Genome U133 Plus 2.0 Array)   229839_at (Human Genome U133 Plus 2.0 Array)   235849_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428663
Ensembl peptide - ENSP00000430713
Ensembl peptide - ENSP00000346990
Ensembl peptide - ENSP00000369746
NCBI entrez gene - 286133     See in Manteia.
OMIM - 611306
RefSeq - NM_173833
RefSeq Peptide - NP_776194
swissprot - Q6ZMJ2
Ensembl - ENSG00000168079
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5RFW0ENSDARG00000010425Danio rerio
 SCARA5ENSGALG00000016580Gallus gallus
 Q8K299ENSMUSG00000022032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSR1 / P21757 / macrophage scavenger receptor 1ENSG0000003894533
MARCO / Q9UEW3 / macrophage receptor with collagenous structureENSG0000001916924
LOXL4 / Q96JB6 / lysyl oxidase like 4ENSG0000013813115
LOXL2 / Q9Y4K0 / lysyl oxidase like 2ENSG0000013401315
LOXL3 / P58215 / lysyl oxidase like 3ENSG0000011531814
CD6 / P30203 / CD6 moleculeENSG0000001372512
LOXL1 / Q08397 / lysyl oxidase like 1ENSG000001290386
LOX / P28300 / lysyl oxidaseENSG000001130832


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR008160  Collagen triple helix repeat
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR017448  SRCR-like domain
 IPR034726  Scavenger receptor class A member 5
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis ISS
 biological_processGO:0006897 endocytosis ISS
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0034755 iron ion transmembrane transport ISS
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:0070207 protein homotrimerization ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0070287 ferritin receptor activity ISS


Pathways (from Reactome)
Pathway description
Scavenging by Class A Receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167996 FTH1 / P02794 / ferritin heavy chain 1  / complex / reaction
 ENSG00000087086 FTL / P02792 / ferritin light chain  / reaction / complex
 ENSG00000168079 Q6ZMJ2 / SCARA5 / scavenger receptor class A member 5  / complex






 

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