ENSMUSG00000026456


Mus musculus

Features
Gene ID: ENSMUSG00000026456
  
Biological name :Cyb5r1
  
Synonyms : Cyb5r1 / cytochrome b5 reductase 1 / Q9DB73
  
Possible biological names infered from orthology : Q9UHQ9
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 134405559
Gene end: 134411740
  
Corresponding Affymetrix probe sets: 10350003 (MoGene1.0st)   1424048_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133842
Ensembl peptide - ENSMUSP00000134354
Ensembl peptide - ENSMUSP00000134488
Ensembl peptide - ENSMUSP00000027726
Ensembl peptide - ENSMUSP00000133385
NCBI entrez gene - 72017     See in Manteia.
MGI - MGI:1919267
RefSeq - NM_028057
RefSeq Peptide - NP_082333
swissprot - Q9DB73
swissprot - G3UXV8
swissprot - G3UZ57
swissprot - G3UZG6
Ensembl - ENSMUSG00000026456
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyb5r1ENSDARG00000018966Danio rerio
 CYB5R1ENSG00000159348Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyb5r3 / Q9DCN2 / NADH-cytochrome b5 reductase 3 NADH-cytochrome b5 reductase 3 membrane-bound form NADH-cytochrome b5 reductase 3 soluble form / P00387* / cytochrome b5 reductase 3*ENSMUSG0000001804258
Cyb5r2 / Q3KNK3 / NADH-cytochrome b5 reductase 2 / Q6BCY4* / cytochrome b5 reductase 2*ENSMUSG0000004806553
Cyb5r4 / Q3TDX8 / Cytochrome b5 reductase 4 / Q7L1T6*ENSMUSG0000003287229


Protein motifs (from Interpro)
Interpro ID Name
 IPR001433  Oxidoreductase FAD/NAD(P)-binding
 IPR001709  Flavoprotein pyridine nucleotide cytochrome reductase
 IPR001834  NADH:cytochrome b5 reductase (CBR)
 IPR008333  Oxidoreductase, FAD-binding domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Erythrocytes take up carbon dioxide and release oxygen


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000069919 Hba-a1 / hemoglobin alpha, adult chain 1 / HBA2* / HBA1* / P69905* / hemoglobin subunit alpha 1* / hemoglobin subunit alpha 2*  / reaction
 ENSMUSG00000073940 Hbb-bt / HBB* / HBD* / P68871* / P02042* / hemoglobin subunit beta* / hemoglobin subunit delta*  / reaction






 

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