ENSMUSG00000048065


Mus musculus

Features
Gene ID: ENSMUSG00000048065
  
Biological name :Cyb5r2
  
Synonyms : Cyb5r2 / NADH-cytochrome b5 reductase 2 / Q3KNK3
  
Possible biological names infered from orthology : cytochrome b5 reductase 2 / Q6BCY4
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 107748455
Gene end: 107758032
  
Corresponding Affymetrix probe sets: 10566632 (MoGene1.0st)   1459448_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050061
Ensembl peptide - ENSMUSP00000146504
NCBI entrez gene - 320635     See in Manteia.
MGI - MGI:2444415
RefSeq - XM_017322305
RefSeq - NM_001205227
RefSeq - NM_177216
RefSeq - XM_006507951
RefSeq - XM_017322303
RefSeq - XM_017322304
RefSeq - XM_006507947
RefSeq - XM_006507948
RefSeq Peptide - NP_796190
RefSeq Peptide - NP_001192156
swissprot - Q3KNK3
Ensembl - ENSMUSG00000048065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyb5r2ENSDARG00000051925Danio rerio
 CYB5R2ENSGALG00000032372Gallus gallus
 CYB5R2ENSG00000166394Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyb5r1 / Q9DB73 / cytochrome b5 reductase 1 / Q9UHQ9*ENSMUSG0000002645656
Cyb5r3 / Q9DCN2 / NADH-cytochrome b5 reductase 3 NADH-cytochrome b5 reductase 3 membrane-bound form NADH-cytochrome b5 reductase 3 soluble form / P00387* / cytochrome b5 reductase 3*ENSMUSG0000001804255
Cyb5r4 / Q3TDX8 / Cytochrome b5 reductase 4 / Q7L1T6*ENSMUSG0000003287226


Protein motifs (from Interpro)
Interpro ID Name
 IPR001433  Oxidoreductase FAD/NAD(P)-binding
 IPR001709  Flavoprotein pyridine nucleotide cytochrome reductase
 IPR001834  NADH:cytochrome b5 reductase (CBR)
 IPR008333  Oxidoreductase, FAD-binding domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane ISO
 molecular_functionGO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H ISO
 molecular_functionGO:0016491 oxidoreductase activity IBA


Pathways (from Reactome)
Pathway description
Erythrocytes take up carbon dioxide and release oxygen


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000069919 Hba-a1 / hemoglobin alpha, adult chain 1 / HBA2* / HBA1* / P69905* / hemoglobin subunit alpha 1* / hemoglobin subunit alpha 2*  / reaction
 ENSMUSG00000073940 Hbb-bt / HBB* / HBD* / P68871* / P02042* / hemoglobin subunit beta* / hemoglobin subunit delta*  / reaction






 

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