ENSMUSG00000026904


Mus musculus

Features
Gene ID: ENSMUSG00000026904
  
Biological name :Slc4a10
  
Synonyms : Q5DTL9 / Slc4a10 / solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
  
Possible biological names infered from orthology : Q6U841 / solute carrier family 4 member 10
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C1.3
Gene start: 62046462
Gene end: 62326730
  
Corresponding Affymetrix probe sets: 10472321 (MoGene1.0st)   1417672_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099796
Ensembl peptide - ENSMUSP00000108099
Ensembl peptide - ENSMUSP00000061411
NCBI entrez gene - 94229     See in Manteia.
MGI - MGI:2150150
RefSeq - NM_001242382
RefSeq - NM_001242383
RefSeq - NM_033552
RefSeq - XM_017319349
RefSeq - NM_001242378
RefSeq - NM_001242379
RefSeq - NM_001242380
RefSeq - NM_001242381
RefSeq - XM_006500448
RefSeq - XM_006500449
RefSeq - XM_006500450
RefSeq - XM_006500451
RefSeq - XM_011239858
RefSeq Peptide - NP_001229311
RefSeq Peptide - NP_291030
RefSeq Peptide - NP_001229310
RefSeq Peptide - NP_001229312
RefSeq Peptide - NP_001229307
RefSeq Peptide - NP_001229308
RefSeq Peptide - NP_001229309
swissprot - Q5DTL9
swissprot - B1AWV9
Ensembl - ENSMUSG00000026904
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc4a10aENSDARG00000063133Danio rerio
 slc4a10bENSDARG00000060303Danio rerio
 SLC4A10ENSGALG00000030032Gallus gallus
 Q6U841ENSG00000144290Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8JZR6 / Slc4a8 / solute carrier family 4 (anion exchanger), member 8 / Q2Y0W8* / solute carrier family 4 member 8*ENSMUSG0000002303274
Slc4a7 / solute carrier family 4, sodium bicarbonate cotransporter, member 7 / Q9Y6M7* / solute carrier family 4 member 7*ENSMUSG0000002173373
O88343 / Slc4a4 / solute carrier family 4 (anion exchanger), member 4 / Q9Y6R1* / solute carrier family 4 member 4*ENSMUSG0000006096150
Slc4a5 / solute carrier family 4 member 5 / Q9BY07*ENSMUSG0000006832344
Slc4a9 / anion exchange protein 4 isoform 5 / Q96Q91* / solute carrier family 4 member 9*ENSMUSG0000002448536
Slc4a2 / solute carrier family 4 (anion exchanger), member 2 / P04920* / solute carrier family 4 member 2*ENSMUSG0000002896235
P16283 / Slc4a3 / solute carrier family 4 (anion exchanger), member 3 / P48751* / solute carrier family 4 member 3*ENSMUSG0000000657635
P04919 / Slc4a1 / solute carrier family 4 (anion exchanger), member 1 / P02730* / solute carrier family 4 member 1 (Diego blood group)*ENSMUSG0000000657429
A2AJN7 / Slc4a11 / Sodium bicarbonate transporter-like protein 11 / Q8NBS3* / solute carrier family 4 member 11*ENSMUSG0000007479619


Protein motifs (from Interpro)
Interpro ID Name
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR003024  Sodium bicarbonate cotransporter
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation ISO
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006885 regulation of pH IDA
 biological_processGO:0009416 response to light stimulus IMP
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0021860 pyramidal neuron development IMP
 biological_processGO:0030641 regulation of cellular pH IMP
 biological_processGO:0035264 multicellular organism growth IMP
 biological_processGO:0035641 locomotory exploration behavior IMP
 biological_processGO:0048854 brain morphogenesis IMP
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:1902600 proton transmembrane transport IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0097440 apical dendrite IDA
 cellular_componentGO:0097441 basal dendrite IDA
 cellular_componentGO:0097442 CA3 pyramidal cell dendrite IDA
 molecular_functionGO:0005452 inorganic anion exchanger activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity IBA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IDA


Pathways (from Reactome)
Pathway description
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000820 abnormal choroid plexus morphology "malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0000822 abnormal brain ventricle morphology "malformed or absent fluid filled cavities of the cerebrum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0001413 abnormal response to new environment "altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0002887 resistance to pharmacologically induced seizures "ability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:77284]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0003461 abnormal response to novel object "altered investigative behavior from controls in reactions associated with exposing an animal to a novel object" [CFG:Center for Functional Genomics, Northwestern University]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0004043 abnormal pH regulation "anomaly in the function of the buffer systems of the body in combination with the respiratory and renal systems that control the relative acidity or alkalinity of the body, as measured by the concentration of hydrogen ion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc26a5mpc234H/Slc26a5mpc234H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrp1rgsc101/Tyrp1rgsc101
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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