ENSMUSG00000027624


Mus musculus

Features
Gene ID: ENSMUSG00000027624
  
Biological name :Epb41l1
  
Synonyms : band 4.1-like protein 1 isoform d / Epb41l1
  
Possible biological names infered from orthology : erythrocyte membrane protein band 4.1 like 1 / Q9H4G0
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 156420909
Gene end: 156543214
  
Corresponding Affymetrix probe sets: 10477854 (MoGene1.0st)   1421090_at (Mouse Genome 430 2.0 Array)   1434575_at (Mouse Genome 430 2.0 Array)   1460592_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105202
Ensembl peptide - ENSMUSP00000099426
Ensembl peptide - ENSMUSP00000105205
Ensembl peptide - ENSMUSP00000154929
Ensembl peptide - ENSMUSP00000121161
Ensembl peptide - ENSMUSP00000029155
Ensembl peptide - ENSMUSP00000099425
NCBI entrez gene - 13821     See in Manteia.
MGI - MGI:103010
RefSeq - XM_017315394
RefSeq - XM_006498714
RefSeq - XM_011239275
RefSeq - XM_011239276
RefSeq - XM_011239277
RefSeq - XM_011239278
RefSeq - XM_011239279
RefSeq - XM_011239280
RefSeq - XM_011239281
RefSeq - XM_017315383
RefSeq - XM_017315393
RefSeq - NM_001006664
RefSeq - NM_001291120
RefSeq - NM_001291121
RefSeq - NM_001291122
RefSeq - NM_001291123
RefSeq - NM_013510
RefSeq - XM_006498708
RefSeq - XM_006498711
RefSeq - XM_006498713
RefSeq Peptide - NP_001006665
RefSeq Peptide - NP_001278050
RefSeq Peptide - NP_001278051
RefSeq Peptide - NP_001278052
RefSeq Peptide - NP_038538
RefSeq Peptide - NP_001278049
swissprot - A2AUK8
swissprot - A2AUK7
swissprot - E9PV14
swissprot - A2AUK5
Ensembl - ENSMUSG00000027624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-178k16.1ENSDARG00000076364Danio rerio
 EPB41L1ENSGALG00000034171Gallus gallus
 Q9H4G0ENSG00000088367Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9WV92 / Epb41l3 / Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed / Q9Y2J2* / erythrocyte membrane protein band 4.1 like 3*ENSMUSG0000002404450
O70318 / Epb41l2 / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA. / O43491* / erythrocyte membrane protein band 4.1 like 2*ENSMUSG0000001997845
Epb41 / P48193 / erythrocyte membrane protein band 4.1 / P11171*ENSMUSG0000002890641
Ptpn4 / Q9WU22 / Tyrosine-protein phosphatase non-receptor type 4 / P29074* / protein tyrosine phosphatase, non-receptor type 4*ENSMUSG0000002638424
Q8BGS1 / Epb41l5 / Band 4.1-like protein 5 / Q9HCM4* / erythrocyte membrane protein band 4.1 like 5*ENSMUSG0000002638321
P52963 / Epb41l4a / Band 4.1-like protein 4A / Q9HCS5* / erythrocyte membrane protein band 4.1 like 4A*ENSMUSG0000002437620
Ptpn3 / A2ALK8 / protein tyrosine phosphatase, non-receptor type 3 / P26045*ENSMUSG0000003876419
Q9JMC8 / Epb41l4b / Band 4.1-like protein 4B / Q9H329* / erythrocyte membrane protein band 4.1 like 4B*ENSMUSG0000002843418
Frmd5 / Q6P5H6 / FERM domain-containing protein 5 / Q7Z6J6* / FERM domain containing 5*ENSMUSG0000002723818
Frmd3 / Q8BHD4 / FERM domain-containing protein 3 / A2A2Y4* / FERM domain containing 3*ENSMUSG0000004912218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR007477  SAB domain
 IPR008379  Band 4.1, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Trafficking of AMPA receptors
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Ptx3tm1Mant/Ptx3tm1Mant
Genetic Background: involves: 129 * C57BL/6J

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
Show

Allelic Composition: Ptx3tm1Mant/Ptx3tm1Mant
Genetic Background: involves: 129 * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptx3tm1Mant/Ptx3tm1Mant
Genetic Background: involves: 129 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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