ENSMUSG00000028434


Mus musculus

Features
Gene ID: ENSMUSG00000028434
  
Biological name :Epb41l4b
  
Synonyms : Band 4.1-like protein 4B / Epb41l4b / Q9JMC8
  
Possible biological names infered from orthology : erythrocyte membrane protein band 4.1 like 4B / Q9H329
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B3
Gene start: 56991972
Gene end: 57143437
  
Corresponding Affymetrix probe sets: 10513112 (MoGene1.0st)   1418294_at (Mouse Genome 430 2.0 Array)   1455628_at (Mouse Genome 430 2.0 Array)   1456570_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092687
Ensembl peptide - ENSMUSP00000030142
Ensembl peptide - ENSMUSP00000037625
NCBI entrez gene - 54357     See in Manteia.
MGI - MGI:1859149
RefSeq - XM_017320318
RefSeq - XM_006538087
RefSeq - XM_006538089
RefSeq - XM_011250068
RefSeq - XM_011250069
RefSeq - NM_019427
RefSeq Peptide - NP_062300
swissprot - B1AXV1
swissprot - A2ALK6
swissprot - Q9JMC8
Ensembl - ENSMUSG00000028434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epb41l4bENSDARG00000061398Danio rerio
 EPB41L4BENSGALG00000029935Gallus gallus
 Q9H329ENSG00000095203Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BGS1 / Epb41l5 / Band 4.1-like protein 5 / Q9HCM4* / erythrocyte membrane protein band 4.1 like 5*ENSMUSG0000002638356
Epb41l1 / band 4.1-like protein 1 isoform d / Q9H4G0* / erythrocyte membrane protein band 4.1 like 1*ENSMUSG0000002762430
O70318 / Epb41l2 / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA. / O43491* / erythrocyte membrane protein band 4.1 like 2*ENSMUSG0000001997830
Q9WV92 / Epb41l3 / Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed / Q9Y2J2* / erythrocyte membrane protein band 4.1 like 3*ENSMUSG0000002404430
Epb41 / P48193 / erythrocyte membrane protein band 4.1 / P11171*ENSMUSG0000002890630
P52963 / Epb41l4a / Band 4.1-like protein 4A / Q9HCS5* / erythrocyte membrane protein band 4.1 like 4A*ENSMUSG0000002437629
Ptpn4 / Q9WU22 / Tyrosine-protein phosphatase non-receptor type 4 / P29074* / protein tyrosine phosphatase, non-receptor type 4*ENSMUSG0000002638428
Frmd3 / Q8BHD4 / FERM domain-containing protein 3 / A2A2Y4* / FERM domain containing 3*ENSMUSG0000004912224
Frmd5 / Q6P5H6 / FERM domain-containing protein 5 / Q7Z6J6* / FERM domain containing 5*ENSMUSG0000002723824
Ptpn3 / A2ALK8 / protein tyrosine phosphatase, non-receptor type 3 / P26045*ENSMUSG0000003876420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR030698  Band 4.1-like protein 4B
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0031032 actomyosin structure organization IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0051549 positive regulation of keratinocyte migration IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0011968 decreased threshold for auditory brainstem response "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith]
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Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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