ENSMUSG00000028419


Mus musculus

Features
Gene ID: ENSMUSG00000028419
  
Biological name :Chmp5
  
Synonyms : Charged multivesicular body protein 5 / Chmp5 / Q9D7S9
  
Possible biological names infered from orthology : Q9NZZ3
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 40948407
Gene end: 40965303
  
Corresponding Affymetrix probe sets: 10504008 (MoGene1.0st)   1432270_a_at (Mouse Genome 430 2.0 Array)   1458572_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030128
NCBI entrez gene - 76959     See in Manteia.
MGI - MGI:1924209
RefSeq - NM_029814
RefSeq Peptide - NP_084090
swissprot - Q9D7S9
Ensembl - ENSMUSG00000028419
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chmp5aENSDARG00000038855Danio rerio
 chmp5bENSDARG00000103718Danio rerio
 CHMP5ENSGALG00000013160Gallus gallus
 CHMP5ENSG00000086065Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000920 cell separation after cytokinesis IEA
 biological_processGO:0001919 regulation of receptor recycling IMP
 biological_processGO:0006997 nucleus organization IEA
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007040 lysosome organization IMP
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0010824 regulation of centrosome duplication IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0046755 viral budding IEA
 biological_processGO:0061763 multivesicular body-lysosome fusion TAS
 biological_processGO:0071985 multivesicular body sorting pathway IEA
 biological_processGO:1901673 regulation of mitotic spindle assembly IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0001688 abnormal somite development "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0001704 abnormal dorsal-ventral axis patterning "anomaly in the development or formation of the axis that runs from the front to the back surface of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0001726 abnormal allantois "malformed fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0002824 abnormal chorioallantoic fusion "abnormal process of or failure of the formation of the membrane that forms the fetal portion of the placenta; derived from the fusion of the chorion and the allantois" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0004187 cardia bifida "failure of the bilateral myocardial cells to coalesce into a single central heart tube resulting in the presence of two independent hearts" [smb:Susan M Bello, Mouse Genome Informatics Curator ""]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0005657 abnormal neural plate morphology "malformation or absence of the neuroectodermal area of the embryo s dorsal surface that develops into the neural tube and neural crest" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator, J:68142]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019868 Vta1 / Q9CR26 / vesicle (multivesicular body) trafficking 1 / Q9NP79* / vesicle trafficking 1*  / complex
 ENSMUSG00000009907 Vps4b / P46467 / vacuolar protein sorting 4B / O75351* / vacuolar protein sorting 4 homolog B*  / complex
 ENSMUSG00000031913 Vps4a / Q8VEJ9 / vacuolar protein sorting 4A / Q9UN37* / AC026464.4* / vacuolar protein sorting 4 homolog A*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr