ENSMUSG00000028708


Mus musculus

Features
Gene ID: ENSMUSG00000028708
  
Biological name :Mknk1
  
Synonyms : MAP kinase-interacting serine/threonine kinase 1 / Mknk1
  
Possible biological names infered from orthology : Q9BUB5
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D1
Gene start: 115839198
Gene end: 115879250
  
Corresponding Affymetrix probe sets: 10507218 (MoGene1.0st)   1417630_at (Mouse Genome 430 2.0 Array)   1417631_at (Mouse Genome 430 2.0 Array)   1454119_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118071
Ensembl peptide - ENSMUSP00000116410
Ensembl peptide - ENSMUSP00000117261
Ensembl peptide - ENSMUSP00000019677
Ensembl peptide - ENSMUSP00000102123
Ensembl peptide - ENSMUSP00000114941
NCBI entrez gene - 17346     See in Manteia.
MGI - MGI:894316
RefSeq - XM_017320015
RefSeq - NM_001285487
RefSeq - NM_001285488
RefSeq - NM_021461
RefSeq - XM_006502822
RefSeq - XM_006502823
RefSeq - XM_006502825
RefSeq Peptide - NP_001272416
RefSeq Peptide - NP_001272417
RefSeq Peptide - NP_067436
swissprot - A2A8W8
swissprot - F6VT22
swissprot - F7B478
swissprot - F6Y5U1
swissprot - F6YIU3
Ensembl - ENSMUSG00000028708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mknk1ENSDARG00000018411Danio rerio
 MKNK1ENSGALG00000010440Gallus gallus
 MKNK1ENSG00000079277Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mknk2 / Q8CDB0 / MAP kinase-interacting serine/threonine-protein kinase 2 / Q9HBH9* / MAP kinase interacting serine/threonine kinase 2*ENSMUSG0000002019072
Q3UMW7 / Mapkapk3 / MAP kinase-activated protein kinase 3 / Q16644* / mitogen-activated protein kinase-activated protein kinase 3*ENSMUSG0000003257729
P49138 / Mapkapk2 / MAP kinase-activated protein kinase 2 / P49137* / mitogen-activated protein kinase-activated protein kinase 2*ENSMUSG0000001652827
Gm42878 / Q8IW41* / MAPKAPK5* / mitogen-activated protein kinase-activated protein kinase 5*ENSMUSG0000010534027
O54992 / Mapkapk5 / MAP kinase-activated protein kinase 5 / Q8IW41* / mitogen-activated protein kinase-activated protein kinase 5*ENSMUSG0000002945427


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Spry regulation of FGF signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdx1tm1Cvw/Pdx1+,Pbx1tm1Mlc/Pbx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Mknk1tm1Fuku/Mknk1tm1Fuku,Mknk2tm1Fuku/Mknk2tm1Fuku
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr