ENSMUSG00000029578


Mus musculus

Features
Gene ID: ENSMUSG00000029578
  
Biological name :Wipi2
  
Synonyms : Q80W47 / WD repeat domain, phosphoinositide interacting 2 / Wipi2
  
Possible biological names infered from orthology : Q9Y4P8
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 142627698
Gene end: 142670588
  
Corresponding Affymetrix probe sets: 10527133 (MoGene1.0st)   1428882_at (Mouse Genome 430 2.0 Array)   1429367_at (Mouse Genome 430 2.0 Array)   1456999_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106405
Ensembl peptide - ENSMUSP00000045201
NCBI entrez gene - 74781     See in Manteia.
MGI - MGI:1923831
RefSeq - NM_178398
RefSeq - XM_006504752
RefSeq Peptide - NP_848485
swissprot - D3YWK1
swissprot - Q80W47
Ensembl - ENSMUSG00000029578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wipi2ENSDARG00000037871Danio rerio
 WIPI2ENSGALG00000004557Gallus gallus
 WIPI2ENSG00000157954Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wipi1 / Q8R3E3 / WD repeat domain, phosphoinositide interacting 1 / Q5MNZ9*ENSMUSG0000004189553


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR032911  WD repeat domain phosphoinositide-interacting protein 2
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006497 protein lipidation IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0034497 protein localization to phagophore assembly site IPI
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0061739 protein lipidation involved in autophagosome assembly IDA
 biological_processGO:0098792 xenophagy IPI
 cellular_componentGO:0000407 phagophore assembly site IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005776 autophagosome IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034045 phagophore assembly site membrane ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding ISO
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026289 Q8C0J2 / Atg16l1 / autophagy related 16-like 1 (S. cerevisiae) / Q676U5* / autophagy related 16 like 1*  / reaction / complex
 ENSMUSG00000038160 Atg5 / Q99J83 / Autophagy protein 5 / Q9H1Y0* / autophagy related 5*  / reaction / complex
 ENSMUSG00000032905 Atg12 / Q9CQY1 / Ubiquitin-like protein ATG12 / O94817* / autophagy related 12*  / complex / reaction






 

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