ENSMUSG00000030411


Mus musculus

Features
Gene ID: ENSMUSG00000030411
  
Biological name :Nova2
  
Synonyms : Nova2 / NOVA alternative splicing regulator 2
  
Possible biological names infered from orthology : Q9UNW9
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 18925888
Gene end: 18965319
  
Corresponding Affymetrix probe sets: 10550514 (MoGene1.0st)   1439099_at (Mouse Genome 430 2.0 Array)   1439192_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032571
Ensembl peptide - ENSMUSP00000151939
NCBI entrez gene - 384569     See in Manteia.
MGI - MGI:104296
RefSeq - NM_001029877
RefSeq Peptide - NP_001025048
swissprot - D3YVV7
swissprot - A0A1W2P872
Ensembl - ENSMUSG00000030411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nova1ENSDARG00000020178Danio rerio
 nova2ENSDARG00000017673Danio rerio
 NOVA2ENSG00000104967Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nova1 / Q9JKN6 / RNA-binding protein Nova-1 / P51513* / NOVA alternative splicing regulator 1*ENSMUSG0000002104773
Hnrnpk / P61979 / Heteroous nuclear ribonucleoprotein K / P61978* / heterogeneous nuclear ribonucleoprotein K*ENSMUSG0000002154622
Pcbp3 / P57722 / Mus musculus poly(rC) binding protein 3 (Pcbp3), transcript variant 2, mRNA. / P57721* / poly(rC) binding protein 3*ENSMUSG0000000112020
Pcbp1 / P60335 / Poly(rC)-binding protein 1 / Q15365*ENSMUSG0000005169520
Pcbp2 / Q61990 / Poly(rC)-binding protein 2 ENSMUSG0000005685120
Pcbp4 / poly(rC) binding protein 4 / P57723*ENSMUSG0000002349519


Protein motifs (from Interpro)
Interpro ID Name
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR033087  RNA-binding protein Nova-2
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0051252 regulation of RNA metabolic process IGI
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002207 abnormal long term potentiation "alterations in a persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ube3atm1Alb/Ube3a+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002945 abnormal inhibitory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Ube3atm1Alb/Ube3a+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ube3atm1Alb/Ube3a+
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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