ENSMUSG00000023495


Mus musculus

Features
Gene ID: ENSMUSG00000023495
  
Biological name :Pcbp4
  
Synonyms : Pcbp4 / poly(rC) binding protein 4
  
Possible biological names infered from orthology : P57723
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F1
Gene start: 106453291
Gene end: 106464012
  
Corresponding Affymetrix probe sets: 10588509 (MoGene1.0st)   1433658_x_at (Mouse Genome 430 2.0 Array)   1449054_a_at (Mouse Genome 430 2.0 Array)   1449055_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024260
Ensembl peptide - ENSMUSP00000150869
Ensembl peptide - ENSMUSP00000149974
Ensembl peptide - ENSMUSP00000149560
Ensembl peptide - ENSMUSP00000149109
Ensembl peptide - ENSMUSP00000148973
Ensembl peptide - ENSMUSP00000148962
Ensembl peptide - ENSMUSP00000141057
Ensembl peptide - ENSMUSP00000140660
Ensembl peptide - ENSMUSP00000140629
Ensembl peptide - ENSMUSP00000140485
Ensembl peptide - ENSMUSP00000139991
Ensembl peptide - ENSMUSP00000139771
Ensembl peptide - ENSMUSP00000139587
NCBI entrez gene - 59092     See in Manteia.
MGI - MGI:1890471
RefSeq - NM_021567
RefSeq - XM_006511779
RefSeq - XM_006511780
RefSeq - XM_006511781
RefSeq - XM_006511782
RefSeq - XM_006511783
RefSeq Peptide - NP_067542
swissprot - A0A087WRJ6
swissprot - A0A087WRH3
swissprot - A0A087WR61
swissprot - A0A1L1SUS5
swissprot - A0A087WPG7
swissprot - A0A087WP16
swissprot - A0A087WQ06
swissprot - A0A1L1SSM1
swissprot - A0A1L1SRP9
swissprot - A0A1L1SQL8
swissprot - A0A1L1SQB0
swissprot - A0A1L1SQ99
swissprot - A0A0R4J044
swissprot - A0A087WSI1
Ensembl - ENSMUSG00000023495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcbp4ENSDARG00000024276Danio rerio
 PCBP4ENSGALG00000027695Gallus gallus
 PCBP4ENSG00000090097Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcbp3 / P57722 / Mus musculus poly(rC) binding protein 3 (Pcbp3), transcript variant 2, mRNA. / P57721* / poly(rC) binding protein 3*ENSMUSG0000000112049
Pcbp2 / Q61990 / Poly(rC)-binding protein 2 ENSMUSG0000005685148
Pcbp1 / P60335 / Poly(rC)-binding protein 1 / Q15365*ENSMUSG0000005169547
Hnrnpk / P61979 / Heteroous nuclear ribonucleoprotein K / P61978* / heterogeneous nuclear ribonucleoprotein K*ENSMUSG0000002154624
Nova1 / Q9JKN6 / RNA-binding protein Nova-1 / P51513* / NOVA alternative splicing regulator 1*ENSMUSG0000002104723
Nova2 / NOVA alternative splicing regulator 2 / Q9UNW9*ENSMUSG0000003041123


Protein motifs (from Interpro)
Interpro ID Name
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR015946  K homology domain-like, alpha/beta
 IPR033088  Poly(rC)-binding protein 4
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043488 regulation of mRNA stability IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Pcbp4Gt(D136D11)Wrst/Pcbp4+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

 MP:0002023 B cell derived lymphoma "heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Pcbp4Gt(D136D11)Wrst/Pcbp4+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002027 lung adenocarcinoma "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Pcbp4Gt(D136D11)Wrst/Pcbp4+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008009 delayed cellular replicative senescence "slower progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

 MP:0010294 increased kidney tumor incidence "greater than the expected number of tumors originating in the kidney in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

Allelic Composition: Pcbp4Gt(D136D11)Wrst/Pcbp4+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Bcortm1Vjba/Y,Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic Background: involves: C57BL/6 * CBA/Ca

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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