ENSMUSG00000031813


Mus musculus

Features
Gene ID: ENSMUSG00000031813
  
Biological name :Mvb12a
  
Synonyms : Multivesicular body subunit 12A / Mvb12a / Q78HU3
  
Possible biological names infered from orthology : Q96EY5
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 71542922
Gene end: 71548085
  
Corresponding Affymetrix probe sets: 10572637 (MoGene1.0st)   1424773_at (Mouse Genome 430 2.0 Array)   1437043_a_at (Mouse Genome 430 2.0 Array)   1455895_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034272
Ensembl peptide - ENSMUSP00000148630
Ensembl peptide - ENSMUSP00000148449
NCBI entrez gene - 73711     See in Manteia.
MGI - MGI:1920961
RefSeq - NM_028617
RefSeq - XM_017312985
RefSeq Peptide - NP_082893
swissprot - A0A1D5RM52
swissprot - Q78HU3
swissprot - A0A1D5RLP2
Ensembl - ENSMUSG00000031813
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MVB12AENSG00000141971Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mvb12b / Q6KAU4 / Multivesicular body subunit 12B / Q9H7P6*ENSMUSG0000003874031


Protein motifs (from Interpro)
Interpro ID Name
 IPR018798  Multivesicular body subunit 12
 IPR023340  UMA domain
 IPR023341  MABP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019075 virus maturation IEA
 biological_processGO:0042058 regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0048524 positive regulation of viral process IEA
 biological_processGO:1903772 regulation of viral budding via host ESCRT complex IEA
 cellular_componentGO:0000813 ESCRT I complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0043130 ubiquitin binding IEA


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014402 Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*  / complex
 ENSMUSG00000031600 Q8CHS8 / Vps37a / vacuolar protein sorting 37A / Q8NEZ2* / VPS37A, ESCRT-I subunit*  / complex
 ENSMUSG00000026718 Stam / P70297 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 / Q92783* / signal transducing adaptor molecule*  / reaction
 ENSMUSG00000048832 Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*  / complex
 ENSMUSG00000043614 Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*  / complex
 ENSMUSG00000006058 Snf8 / Q9CZ28 / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q96H20* / SNF8, ESCRT-II complex subunit*  / reaction
 ENSMUSG00000055371 Stam2 / O88811 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 / O75886* / signal transducing adaptor molecule 2*  / reaction
 ENSMUSG00000078656 Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*  / reaction
 ENSMUSG00000115987 Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*  / complex
 ENSMUSG00000031479 Vps36 / Q91XD6 / vacuolar protein sorting 36 / Q86VN1* / vacuolar protein sorting 36 homolog*  / reaction
 ENSMUSG00000066278 Q8R0J7 / Vps37b / vacuolar protein sorting 37B / Q9H9H4* / VPS37B, ESCRT-I subunit*  / complex






 

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