ENSMUSG00000031479


Mus musculus

Features
Gene ID: ENSMUSG00000031479
  
Biological name :Vps36
  
Synonyms : Q91XD6 / vacuolar protein sorting 36 / Vps36
  
Possible biological names infered from orthology : Q86VN1 / vacuolar protein sorting 36 homolog
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A2
Gene start: 22192809
Gene end: 22220843
  
Corresponding Affymetrix probe sets: 10570771 (MoGene1.0st)   1424417_at (Mouse Genome 430 2.0 Array)   1451343_at (Mouse Genome 430 2.0 Array)   1452898_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033866
NCBI entrez gene - 70160     See in Manteia.
MGI - MGI:1917410
RefSeq - NM_027338
RefSeq Peptide - NP_081614
swissprot - Q3TSR1
swissprot - Q91XD6
Ensembl - ENSMUSG00000031479
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps36ENSDARG00000057021Danio rerio
 VPS36ENSGALG00000017026Gallus gallus
 VPS36ENSG00000136100Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011993  PH-like domain superfamily
 IPR021648  Vacuolar protein sorting protein 36, GLUE domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport IC
 biological_processGO:0032509 endosome transport via multivesicular body sorting pathway IEA
 biological_processGO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
 cellular_componentGO:0000814 ESCRT II complex ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0043130 ubiquitin binding ISO


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014402 Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*  / reaction
 ENSMUSG00000066278 Q8R0J7 / Vps37b / vacuolar protein sorting 37B / Q9H9H4* / VPS37B, ESCRT-I subunit*  / reaction
 ENSMUSG00000031813 Mvb12a / Q78HU3 / Multivesicular body subunit 12A / Q96EY5*  / reaction
 ENSMUSG00000006058 Snf8 / Q9CZ28 / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q96H20* / SNF8, ESCRT-II complex subunit*  / complex
 ENSMUSG00000078656 Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*  / complex
 ENSMUSG00000038740 Mvb12b / Q6KAU4 / Multivesicular body subunit 12B / Q9H7P6*  / reaction
 ENSMUSG00000043614 Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*  / reaction
 ENSMUSG00000028437 Ubap1 / Q8BH48 / ubiquitin-associated protein 1 / Q9NZ09*  / reaction
 ENSMUSG00000048832 Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*  / reaction
 ENSMUSG00000115987 Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*  / reaction
 ENSMUSG00000031600 Q8CHS8 / Vps37a / vacuolar protein sorting 37A / Q8NEZ2* / VPS37A, ESCRT-I subunit*  / reaction






 

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