ENSMUSG00000038740


Mus musculus

Features
Gene ID: ENSMUSG00000038740
  
Biological name :Mvb12b
  
Synonyms : Multivesicular body subunit 12B / Mvb12b / Q6KAU4
  
Possible biological names infered from orthology : Q9H7P6
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 33729953
Gene end: 33887946
  
Corresponding Affymetrix probe sets: 10481845 (MoGene1.0st)   1428121_at (Mouse Genome 430 2.0 Array)   1428122_s_at (Mouse Genome 430 2.0 Array)   1428123_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048901
Ensembl peptide - ENSMUSP00000115744
NCBI entrez gene - 72543     See in Manteia.
MGI - MGI:1919793
RefSeq - XM_011239194
RefSeq - NM_175184
RefSeq - XM_006498371
RefSeq - XM_006498372
RefSeq - XM_006498373
RefSeq - XM_006498367
RefSeq - XM_006498368
RefSeq - XM_006498369
RefSeq - XM_006498370
RefSeq Peptide - NP_780393
swissprot - Q6KAU4
swissprot - A2ARF0
Ensembl - ENSMUSG00000038740
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mvb12baENSDARG00000091619Danio rerio
 MVB12BENSGALG00000000950Gallus gallus
 MVB12BENSG00000196814Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mvb12a / Q78HU3 / Multivesicular body subunit 12A / Q96EY5*ENSMUSG0000003181326


Protein motifs (from Interpro)
Interpro ID Name
 IPR018798  Multivesicular body subunit 12
 IPR023340  UMA domain
 IPR023341  MABP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019075 virus maturation IEA
 biological_processGO:0042058 regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0048524 positive regulation of viral process IEA
 cellular_componentGO:0000813 ESCRT I complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014402 Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*  / complex
 ENSMUSG00000026718 Stam / P70297 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 / Q92783* / signal transducing adaptor molecule*  / reaction
 ENSMUSG00000031479 Vps36 / Q91XD6 / vacuolar protein sorting 36 / Q86VN1* / vacuolar protein sorting 36 homolog*  / reaction
 ENSMUSG00000055371 Stam2 / O88811 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 / O75886* / signal transducing adaptor molecule 2*  / reaction
 ENSMUSG00000078656 Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*  / reaction
 ENSMUSG00000043614 Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*  / complex
 ENSMUSG00000006058 Snf8 / Q9CZ28 / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q96H20* / SNF8, ESCRT-II complex subunit*  / reaction
 ENSMUSG00000115987 Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*  / complex
 ENSMUSG00000066278 Q8R0J7 / Vps37b / vacuolar protein sorting 37B / Q9H9H4* / VPS37B, ESCRT-I subunit*  / complex
 ENSMUSG00000031600 Q8CHS8 / Vps37a / vacuolar protein sorting 37A / Q8NEZ2* / VPS37A, ESCRT-I subunit*  / complex
 ENSMUSG00000048832 Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr