ENSMUSG00000032264


Mus musculus

Features
Gene ID: ENSMUSG00000032264
  
Biological name :Zw10
  
Synonyms : O54692 / Zw10 / zw10 kinetochore protein
  
Possible biological names infered from orthology : O43264
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.3
Gene start: 49055613
Gene end: 49078775
  
Corresponding Affymetrix probe sets: 10585129 (MoGene1.0st)   1424891_a_at (Mouse Genome 430 2.0 Array)   1431747_at (Mouse Genome 430 2.0 Array)   1441888_x_at (Mouse Genome 430 2.0 Array)   1445206_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150032
Ensembl peptide - ENSMUSP00000034803
NCBI entrez gene - 26951     See in Manteia.
MGI - MGI:1349478
RefSeq - NM_012039
RefSeq - XM_006510371
RefSeq Peptide - NP_036169
swissprot - A0A1L1SST9
swissprot - O54692
Ensembl - ENSMUSG00000032264
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zw10ENSDARG00000018738Danio rerio
 ZW10ENSGALG00000040155Gallus gallus
 ZW10ENSG00000086827Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009361  RZZ complex, subunit Zw10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IEA
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0007093 mitotic cell cycle checkpoint IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IBA
 biological_processGO:0007096 regulation of exit from mitosis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034501 protein localization to kinetochore IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore ISS
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005828 kinetochore microtubule IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070939 Dsl1/NZR complex IEA
 cellular_componentGO:1990423 RZZ complex IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
COPI-dependent Golgi-to-ER retrograde traffic
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024191 Bnip1 / Q6QD59 / Vesicle transport protein SEC20 / Q12981* / BCL2 interacting protein 1*  / reaction
 ENSMUSG00000002395 Use1 / Q9CQ56 / unconventional SNARE in the ER 1 homolog (S. cerevisiae) / Q9NZ43* / unconventional SNARE in the ER 1*  / reaction
 ENSMUSG00000029125 Stx18 / Q8VDS8 / Syntaxin-18 / Q9P2W9*  / reaction
 ENSMUSG00000020576 Nbas / neuroblastoma amplified sequence / A2RRP1*  / complex
 ENSMUSG00000028999 Rint1 / Q8BZ36 / RAD50 interactor 1 / Q6NUQ1*  / complex
 ENSMUSG00000029414 Kntc1 / Q8C3Y4 / Kinetochore-associated protein 1 / P50748* / kinetochore associated 1*  / complex






 

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