ENSMUSG00000032413


Mus musculus

Features
Gene ID: ENSMUSG00000032413
  
Biological name :Rasa2
  
Synonyms : P58069 / Rasa2 / Ras GTPase-activating protein 2
  
Possible biological names infered from orthology : Q15283 / RAS p21 protein activator 2
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 96539300
Gene end: 96631617
  
Corresponding Affymetrix probe sets: 10595805 (MoGene1.0st)   1422785_at (Mouse Genome 430 2.0 Array)   1455181_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034984
Ensembl peptide - ENSMUSP00000115629
NCBI entrez gene - 114713     See in Manteia.
MGI - MGI:2149960
RefSeq - XM_017313108
RefSeq - NM_053268
RefSeq - XM_006510775
RefSeq - XM_006510776
RefSeq Peptide - NP_444498
swissprot - D3YZE9
swissprot - P58069
Ensembl - ENSMUSG00000032413
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01005876.1ENSDARG00000078775Danio rerio
 RASA2ENSGALG00000002850Gallus gallus
 RASA2ENSG00000155903Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rasa3 / Q60790 / Ras GTPase-activating protein 3 / Q14644* / RAS p21 protein activator 3*ENSMUSG0000003145358
Rasa4 / Q6PFQ7 / RAS p21 protein activator 4 / C9J798* / O43374* / RASA4B* / RAS p21 protein activator 4B*ENSMUSG0000000495228
Q9Z268 / Rasal1 / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcript variant 3, mRNA. / O95294* / RAS protein activator like 1*ENSMUSG0000002960227
F6SEU4 / Syngap1 / Ras/Rap GTPase-activating protein SynGAP / Q96PV0* / synaptic Ras GTPase activating protein 1*ENSMUSG0000006762919
Dab2ip / Q3UHC7 / Disabled homolog 2-interacting protein / Q5VWQ8* / DAB2 interacting protein*ENSMUSG0000002688318
Rasal2 / RAS protein activator like 2 / Q9UJF2*ENSMUSG0000007056518
Rasa1 / RAS p21 protein activator 1 / P20936*ENSMUSG0000002154914
Q8C2K5 / Rasal3 / RAS protein activator like 3 / Q86YV0*ENSMUSG0000005214214


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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