ENSMUSG00000029602


Mus musculus

Features
Gene ID: ENSMUSG00000029602
  
Biological name :Rasal1
  
Synonyms : Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcript variant 3, mRNA. / Q9Z268 / Rasal1
  
Possible biological names infered from orthology : O95294 / RAS protein activator like 1
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 120648812
Gene end: 120679597
  
Corresponding Affymetrix probe sets: 10525134 (MoGene1.0st)   1417858_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031606
Ensembl peptide - ENSMUSP00000119913
Ensembl peptide - ENSMUSP00000123266
NCBI entrez gene - 19415     See in Manteia.
MGI - MGI:1330842
RefSeq - XM_017320741
RefSeq - NM_001281999
RefSeq - NM_001359144
RefSeq - NM_013832
RefSeq - XM_017320736
RefSeq - XM_017320737
RefSeq - XM_017320738
RefSeq - XM_017320739
RefSeq - XM_017320740
RefSeq - XM_006530208
RefSeq - XM_006530209
RefSeq - XM_006530210
RefSeq - XM_017320734
RefSeq - XM_017320735
RefSeq Peptide - NP_001268928
RefSeq Peptide - NP_001346073
RefSeq Peptide - NP_038860
swissprot - Q9Z268
swissprot - D3Z7V8
Ensembl - ENSMUSG00000029602
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rasal1bENSDARG00000041515Danio rerio
 RASAL1ENSGALG00000008150Gallus gallus
 O95294ENSG00000111344Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rasa4 / Q6PFQ7 / RAS p21 protein activator 4 / C9J798* / O43374* / RASA4B* / RAS p21 protein activator 4B*ENSMUSG0000000495247
Rasa3 / Q60790 / Ras GTPase-activating protein 3 / Q14644* / RAS p21 protein activator 3*ENSMUSG0000003145332
Rasa2 / P58069 / Ras GTPase-activating protein 2 / Q15283* / RAS p21 protein activator 2*ENSMUSG0000003241329
Rasal2 / RAS protein activator like 2 / Q9UJF2*ENSMUSG0000007056522
F6SEU4 / Syngap1 / Ras/Rap GTPase-activating protein SynGAP / Q96PV0* / synaptic Ras GTPase activating protein 1*ENSMUSG0000006762922
Dab2ip / Q3UHC7 / Disabled homolog 2-interacting protein / Q5VWQ8* / DAB2 interacting protein*ENSMUSG0000002688321
Q8C2K5 / Rasal3 / RAS protein activator like 3 / Q86YV0*ENSMUSG0000005214218
Rasa1 / RAS p21 protein activator 1 / P20936*ENSMUSG0000002154916


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR028555  RasGAP-activating-like protein 1
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:1903861 positive regulation of dendrite extension IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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