ENSMUSG00000033364


Mus musculus

Features
Gene ID: ENSMUSG00000033364
  
Biological name :Usp37
  
Synonyms : Q8C0R0 / ubiquitin specific peptidase 37 / Usp37
  
Possible biological names infered from orthology : Q86T82
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C3
Gene start: 74435511
Gene end: 74544284
  
Corresponding Affymetrix probe sets: 10355582 (MoGene1.0st)   1434242_at (Mouse Genome 430 2.0 Array)   1438212_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140670
Ensembl peptide - ENSMUSP00000035445
Ensembl peptide - ENSMUSP00000140158
NCBI entrez gene - 319651     See in Manteia.
MGI - MGI:2442483
RefSeq - XM_006496057
RefSeq - NM_001310662
RefSeq - NM_176972
RefSeq - XM_006496054
RefSeq Peptide - NP_001297591
RefSeq Peptide - NP_795946
swissprot - A0A0R4J2D0
swissprot - Q8C0R0
swissprot - A0A087WQE4
Ensembl - ENSMUSG00000033364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp37ENSDARG00000040990Danio rerio
 USP37ENSGALG00000011427Gallus gallus
 USP37ENSG00000135913Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp29 / Q9ES63 / ubiquitin specific peptidase 29 / Q9HBJ7*ENSMUSG0000005152730
Usp26 / Q99MX1 / ubiquitin specific peptidase 26 / Q9BXU7*ENSMUSG0000005578026


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR003903  Ubiquitin interacting motif
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR032069  Ubiquitin carboxyl-terminal hydrolase 37, pleckstrin homology-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0006275 regulation of DNA replication IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0035871 protein K11-linked deubiquitination IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Lynm2Anu/Lynm2Anu
Genetic Background: C57B/6JAnu-Lynm2Anu/AnuApb

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030079 P60122 / Ruvbl1 / RuvB-like protein 1 / Q9Y265* / RuvB like AAA ATPase 1*  / complex
 ENSMUSG00000020708 Psmc5 / P62196 / protease (prosome, macropain) 26S subunit, ATPase 5 / P62195* / proteasome 26S subunit, ATPase 5*  / complex
 ENSMUSG00000027793 Ccna1 / Q61456 / Cyclin-A1 / P78396*  / complex
 ENSMUSG00000027715 Ccna2 / P51943 / Cyclin-A2 / P20248*  / complex






 

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