ENSMUSG00000034724


Mus musculus

Features
Gene ID: ENSMUSG00000034724
  
Biological name :Cnot6l
  
Synonyms : CCR4-NOT transcription complex subunit 6-like / Cnot6l / Q8VEG6
  
Possible biological names infered from orthology : Q96LI5
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E3
Gene start: 96070333
Gene end: 96164171
  
Corresponding Affymetrix probe sets: 10531529 (MoGene1.0st)   1425480_at (Mouse Genome 430 2.0 Array)   1425481_at (Mouse Genome 430 2.0 Array)   1434311_at (Mouse Genome 430 2.0 Array)   1451723_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116326
Ensembl peptide - ENSMUSP00000114436
Ensembl peptide - ENSMUSP00000119415
Ensembl peptide - ENSMUSP00000123653
Ensembl peptide - ENSMUSP00000121627
Ensembl peptide - ENSMUSP00000047522
Ensembl peptide - ENSMUSP00000108629
Ensembl peptide - ENSMUSP00000113821
NCBI entrez gene - 231464     See in Manteia.
MGI - MGI:2443154
RefSeq - XM_006534872
RefSeq - NM_001285511
RefSeq - NM_001285514
RefSeq - NM_144910
RefSeq - NM_178854
RefSeq - XM_006534870
RefSeq - XM_006534871
RefSeq Peptide - NP_001272440
RefSeq Peptide - NP_001272443
RefSeq Peptide - NP_659159
RefSeq Peptide - NP_849185
swissprot - F8WJG1
swissprot - D3YXZ0
swissprot - D3Z2G5
swissprot - D3YVH6
swissprot - D3Z5R3
swissprot - Q8VEG6
Ensembl - ENSMUSG00000034724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A2BHJ4ENSDARG00000054597Danio rerio
 CNOT6LENSGALG00000010333Gallus gallus
 CNOT6LENSG00000138767Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cnot6 / Q8K3P5 / CCR4-NOT transcription complex subunit 6 / Q9ULM6*ENSMUSG0000002036277
1 / Angel1 / Q8VCU0 / Q9UNK9* / angel homolog 1*ENSMUSG0000002125722
Angel2 / Q8K1C0 / Mus musculus angel homolog 2 (Angel2), transcript variant 3, mRNA. / Q5VTE6* / angel homolog 2*ENSMUSG0000002663421
Pde12 / Q3TIU4 / 2,5-phosphodiesterase 12 / Q6L8Q7* / phosphodiesterase 12*ENSMUSG0000004370220
Noct / O35710 / Nocturnin / Q9UK39*ENSMUSG0000002308718


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR032675  Leucine-rich repeat domain superfamily
 IPR034967  CCR4-NOT transcription complex subunit 6-like
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010606 positive regulation of cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0061157 mRNA destabilization IMP
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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