ENSMUSG00000036902


Mus musculus

Features
Gene ID: ENSMUSG00000036902
  
Biological name :Neto2
  
Synonyms : Mus musculus neuropilin (NRP) and tolloid (TLL)-like 2 (Neto2), transcript variant 1, mRNA. / Neto2 / Q8BNJ6
  
Possible biological names infered from orthology : neuropilin and tolloid like 2 / Q8NC67
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C3
Gene start: 85636588
Gene end: 85700924
  
Corresponding Affymetrix probe sets: 10580382 (MoGene1.0st)   1436309_at (Mouse Genome 430 2.0 Array)   1454032_at (Mouse Genome 430 2.0 Array)   1457344_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105308
Ensembl peptide - ENSMUSP00000148172
Ensembl peptide - ENSMUSP00000150062
NCBI entrez gene - 74513     See in Manteia.
MGI - MGI:1921763
RefSeq - XM_011248528
RefSeq - NM_001081324
RefSeq - NM_001357287
RefSeq - NM_001357288
RefSeq - XM_006531437
RefSeq - XM_006531439
RefSeq - XM_006531440
RefSeq Peptide - NP_001074793
RefSeq Peptide - NP_001344216
RefSeq Peptide - NP_001344217
swissprot - Q8BNJ6
swissprot - B2RXQ6
Ensembl - ENSMUSG00000036902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neto2bENSDARG00000063293Danio rerio
 neto2bENSDARG00000112100Danio rerio
 NETO2ENSGALG00000004071Gallus gallus
 NETO2ENSG00000171208Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Neto1 / Q8R4I7 / Neuropilin and tolloid-like protein 1 / Q8TDF5* / neuropilin and tolloid like 1*ENSMUSG0000005032153
Cubn / Q9JLB4 / Cubilin / O60494*ENSMUSG0000002672623
Tll2 / Q9WVM6 / Tolloid-like protein 2 / Q9Y6L7* / tolloid like 2*ENSMUSG0000002501321
Tll1 / tolloid-like / O43897* / tolloid like 1*ENSMUSG0000005362621
Bmp1 / P98063 / Bone morphotic protein 1 / P13497* / bone morphogenetic protein 1*ENSMUSG0000002209821
Mfrp / Q8K480 / Membrane frizzled-related protein / Q9BY79*ENSMUSG0000003473916
Cdcp2 / Q8BQH6 / CUB domain-containing protein 2 / Q5VXM1*ENSMUSG0000004763615
Pcolce / Q61398 / Procollagen C-endopeptidase enhancer 1 / Q15113* / procollagen C-endopeptidase enhancer*ENSMUSG0000002971813
Q8R4W6 / Pcolce2 / Procollagen C-endopeptidase enhancer 2 / Q9UKZ9*ENSMUSG0000001535412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR028868  Neuropilin and tolloid-like protein 2
 IPR035914  Spermadhesin, CUB domain superfamily
 IPR036055  LDL receptor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:2000312 regulation of kainate selective glutamate receptor activity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002910 abnormal excitatory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Tet2tm1.1Iaai/Tet2tm1.1Iaai,Tg(Vav1-cre)1Graf/0
Genetic Background: involves: 129S/SvEv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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