ENSMUSG00000015354


Mus musculus

Features
Gene ID: ENSMUSG00000015354
  
Biological name :Pcolce2
  
Synonyms : Pcolce2 / Procollagen C-endopeptidase enhancer 2 / Q8R4W6
  
Possible biological names infered from orthology : Q9UKZ9
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 95637601
Gene end: 95698096
  
Corresponding Affymetrix probe sets: 10587880 (MoGene1.0st)   1451527_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015498
NCBI entrez gene - 76477     See in Manteia.
MGI - MGI:1923727
RefSeq - NM_029620
RefSeq Peptide - NP_083896
swissprot - Q8R4W6
Ensembl - ENSMUSG00000015354
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcolce2aENSDARG00000008450Danio rerio
 pimr62ENSDARG00000055575Danio rerio
 PCOLCE2ENSGALG00000002623Gallus gallus
 Q9UKZ9ENSG00000163710Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcolce / Q61398 / Procollagen C-endopeptidase enhancer 1 / Q15113* / procollagen C-endopeptidase enhancer*ENSMUSG0000002971848
Cubn / Q9JLB4 / Cubilin / O60494*ENSMUSG0000002672628
Tll1 / tolloid-like / O43897* / tolloid like 1*ENSMUSG0000005362627
Tll2 / Q9WVM6 / Tolloid-like protein 2 / Q9Y6L7* / tolloid like 2*ENSMUSG0000002501327
Bmp1 / P98063 / Bone morphotic protein 1 / P13497* / bone morphogenetic protein 1*ENSMUSG0000002209825
Cdcp2 / Q8BQH6 / CUB domain-containing protein 2 / Q5VXM1*ENSMUSG0000004763625
Mfrp / Q8K480 / Membrane frizzled-related protein / Q9BY79*ENSMUSG0000003473922
Neto1 / Q8R4I7 / Neuropilin and tolloid-like protein 1 / Q8TDF5* / neuropilin and tolloid like 1*ENSMUSG0000005032117
Neto2 / Q8BNJ6 / Mus musculus neuropilin (NRP) and tolloid (TLL)-like 2 (Neto2), transcript variant 1, mRNA. / Q8NC67* / neuropilin and tolloid like 2*ENSMUSG0000003690216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR018933  Netrin module, non-TIMP type
 IPR035814  Procollagen C-endopeptidase enhancer, NTR domain
 IPR035914  Spermadhesin, CUB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016504 peptidase activator activity IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cacna1smdg/Cacna1smdg
Genetic Background: involves: 129 * STOCK T/t4

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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