ENSG00000163710


Homo sapiens

Features
Gene ID: ENSG00000163710
  
Biological name :PCOLCE2
  
Synonyms : PCOLCE2 / procollagen C-endopeptidase enhancer 2 / Q9UKZ9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q23
Gene start: 142815922
Gene end: 142889203
  
Corresponding Affymetrix probe sets: 219295_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418782
Ensembl peptide - ENSP00000419842
Ensembl peptide - ENSP00000419643
Ensembl peptide - ENSP00000295992
NCBI entrez gene - 26577     See in Manteia.
OMIM - 607064
RefSeq - NM_013363
RefSeq Peptide - NP_037495
swissprot - Q9UKZ9
swissprot - H7C5D5
swissprot - H7C520
swissprot - C9JYX9
Ensembl - ENSG00000163710
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcolce2aENSDARG00000008450Danio rerio
 pimr62ENSDARG00000055575Danio rerio
 PCOLCE2ENSGALG00000002623Gallus gallus
 Q8R4W6ENSMUSG00000015354Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCOLCE / Q15113 / procollagen C-endopeptidase enhancerENSG0000010633346
CUBN / O60494 / cubilinENSG0000010761129
TLL1 / O43897 / tolloid like 1ENSG0000003829526
TLL2 / Q9Y6L7 / tolloid like 2ENSG0000009558726
CDCP2 / Q5VXM1 / CUB domain containing protein 2ENSG0000015721126
BMP1 / P13497 / bone morphogenetic protein 1ENSG0000016848725
MFRP / Q9BY79 / membrane frizzled-related proteinENSG0000023571821
NETO1 / Q8TDF5 / neuropilin and tolloid like 1ENSG0000016634216
NETO2 / Q8NC67 / neuropilin and tolloid like 2ENSG0000017120816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001134  Netrin domain
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR018933  Netrin module, non-TIMP type
 IPR035814  Procollagen C-endopeptidase enhancer, NTR domain
 IPR035914  Spermadhesin, CUB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0016504 peptidase activator activity IDA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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