ENSMUSG00000038844


Mus musculus

Features
Gene ID: ENSMUSG00000038844
  
Biological name :Kif16b
  
Synonyms : B1AVY7 / Kif16b / Kinesin-like protein KIF16B
  
Possible biological names infered from orthology : kinesin family member 16B / Q96L93
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: G1
Gene start: 142617474
Gene end: 142901531
  
Corresponding Affymetrix probe sets: 10488156 (MoGene1.0st)   1429062_at (Mouse Genome 430 2.0 Array)   1429063_s_at (Mouse Genome 430 2.0 Array)   1458694_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042551
Ensembl peptide - ENSMUSP00000154926
Ensembl peptide - ENSMUSP00000148731
Ensembl peptide - ENSMUSP00000148706
NCBI entrez gene - 16558     See in Manteia.
MGI - MGI:1098240
RefSeq - XM_006498813
RefSeq - XM_006498814
RefSeq - XM_006498818
RefSeq - XM_006498817
RefSeq - NM_001081133
RefSeq - XM_006498819
RefSeq - XM_006498815
RefSeq Peptide - NP_001342052
RefSeq Peptide - NP_001074602
swissprot - E7FLY0
swissprot - A0A1D5RMB3
swissprot - A0A1D5RMD4
swissprot - B1AVY7
Ensembl - ENSMUSG00000038844
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif16baENSDARG00000100225Danio rerio
 kif16bbENSDARG00000080018Danio rerio
 KIF16BENSGALG00000008725Gallus gallus
 KIF16BENSG00000089177Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif13a / kinesin family member 13A / Q9H1H9*ENSMUSG0000002137529
Kif13b / kinesin family member 13B / Q9NQT8*ENSMUSG0000006001228
Q80TF6 / Stard9 / StAR-related lipid transfer protein 9 / Q9P2P6* / StAR related lipid transfer domain containing 9*ENSMUSG0000003370528
Kif1a / kinesin family member 1A / Q12756*ENSMUSG0000001460228
Kif1b / Q60575 / Kinesin-like protein KIF1B / O60333* / kinesin family member 1B*ENSMUSG0000006307728
Kif14 / L0N7N1 / Kinesin-like protein KIF14 / Q15058* / kinesin family member 14*ENSMUSG0000004149826
Kif1c / O35071 / Kinesin-like protein KIF1C / O43896* / kinesin family member 1C*ENSMUSG0000002082123
Kif28ENSMUSG0000008723619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001683  Phox homologous domain
 IPR001752  Kinesin motor domain
 IPR008984  SMAD/FHA domain superfamily
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036871  PX domain superfamily
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001704 formation of primary germ layer IMP
 biological_processGO:0001919 regulation of receptor recycling IEA
 biological_processGO:0006895 Golgi to endosome transport IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0007492 endoderm development IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0032801 receptor catabolic process IEA
 biological_processGO:0045022 early endosome to late endosome transport IEA
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: a/a,Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic Background: involves: C57BL/6 * KK

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: a/a,Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic Background: involves: C57BL/6 * KK

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: a/a,Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic Background: involves: C57BL/6 * KK

 MP:0011183 abnormal primitive endoderm morphology "any structural anomaly of the monolayer of cells derived from and located on the surface of inner cell mass, directly facing the blastocoele, and is separated from the more centrally located epiblast by basal lamina; the primitive endoderm give rises to the visceral endoderm and the parietal endoderm" [PMID:21123814]
Show

Allelic Composition: a/a,Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic Background: involves: C57BL/6 * KK

 MP:0011184 absent embryonic epiblast "absence of the tissue derived from the inner cell mass that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper and to the extraembryonic mesoderm" [PMID:21123814]
Show

Allelic Composition: a/a,Rmi1Gt(pUHachi)0283Imeg/Rmi1+
Genetic Background: involves: C57BL/6 * KK

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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