ENSMUSG00000060012


Mus musculus

Features
Gene ID: ENSMUSG00000060012
  
Biological name :Kif13b
  
Synonyms : Kif13b / kinesin family member 13B
  
Possible biological names infered from orthology : Q9NQT8
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D1
Gene start: 64647265
Gene end: 64809617
  
Corresponding Affymetrix probe sets: 10415911 (MoGene1.0st)   1433158_at (Mouse Genome 430 2.0 Array)   1433159_at (Mouse Genome 430 2.0 Array)   1436056_at (Mouse Genome 430 2.0 Array)   1453276_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098041
Ensembl peptide - ENSMUSP00000153252
Ensembl peptide - ENSMUSP00000153168
NCBI entrez gene - 16554     See in Manteia.
MGI - MGI:1098265
RefSeq - XM_017315888
RefSeq - XM_006518619
RefSeq - XM_006518620
RefSeq - XM_006518621
RefSeq - XM_006518622
RefSeq - NM_001081177
RefSeq Peptide - NP_001074646
swissprot - A0A286YD28
swissprot - A0A286YCV9
swissprot - E9Q4K7
Ensembl - ENSMUSG00000060012
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif13baENSDARG00000079731Danio rerio
 kif13bbENSDARG00000073859Danio rerio
 ENSGALG00000035097Gallus gallus
 KIF13BENSG00000197892Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif13a / kinesin family member 13A / Q9H1H9*ENSMUSG0000002137553
Kif1b / Q60575 / Kinesin-like protein KIF1B / O60333* / kinesin family member 1B*ENSMUSG0000006307728
Kif1a / kinesin family member 1A / Q12756*ENSMUSG0000001460227
Q80TF6 / Stard9 / StAR-related lipid transfer protein 9 / Q9P2P6* / StAR related lipid transfer domain containing 9*ENSMUSG0000003370522
Kif14 / L0N7N1 / Kinesin-like protein KIF14 / Q15058* / kinesin family member 14*ENSMUSG0000004149821
Kif1c / O35071 / Kinesin-like protein KIF1C / O43896* / kinesin family member 1C*ENSMUSG0000002082120
B1AVY7 / Kif16b / Kinesin-like protein KIF16B / Q96L93* / kinesin family member 16B*ENSMUSG0000003884420
Kif28ENSMUSG0000008723617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR000938  CAP Gly-rich domain
 IPR001752  Kinesin motor domain
 IPR008984  SMAD/FHA domain superfamily
 IPR019821  Kinesin motor domain, conserved site
 IPR022140  Kinesin-like KIF1-type
 IPR022164  Kinesin-like
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR032405  Kinesin-associated
 IPR035892  C2 domain superfamily
 IPR036859  CAP Gly-rich domain superfamily
 IPR036961  Kinesin motor domain superfamily
 IPR036978  Kinesin-like protein KIF13B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 biological_processGO:0050770 regulation of axonogenesis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0033270 paranode region of axon IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000182 increased circulating LDL cholesterol level "greater than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
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Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0012329 increased circulating factor VIII level "greater levels of the antihemophilic factor that is part of the factor VIII/von Willebrand factor complex; it is produced in the liver and acts in the intrinsic pathway of blood coagulation; it serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin" [MeSH:D12.776.124.125.350, MPD:Molly]
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Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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